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Purpose: To develop a scan-specific model that estimates and corrects k-space errors made when reconstructing accelerated Magnetic Resonance Imaging (MRI) data. Methods: Scan-Specific Artifact Reduction in k-space (SPARK) trains a convolutional-neural-network to estimate and correct k-space errors made by an input reconstruction technique by back-propagating from the mean-squared-error loss between an auto-calibration signal (ACS) and the input techniques reconstructed ACS. First, SPARK is applied to GRAPPA and demonstrates improved robustness over other scan-specific models, such as RAKI and residual-RAKI. Subsequent experiments demonstrate that SPARK synergizes with residual-RAKI to improve reconstruction performance. SPARK also improves reconstruction quality when applied to advanced acquisition and reconstruction techniques like 2D virtual coil (VC-) GRAPPA, 2D LORAKS, 3D GRAPPA without an integrated ACS region, and 2D/3D wave-encoded images. Results: SPARK yields 1.5x - 2x RMSE reduction when applied to GRAPPA and improves robustness to ACS size for various acceleration rates in comparison to other scan-specific techniques. When applied to advanced reconstruction techniques such as residual-RAKI, 2D VC-GRAPPA and LORAKS, SPARK achieves up to 20% RMSE improvement. SPARK with 3D GRAPPA also improves performance by ~2x and perceived image quality without a fully sampled ACS region. Finally, SPARK synergizes with non-cartesian 2D and 3D wave-encoding imaging by reducing RMSE between 20-25% and providing qualitative improvements. Conclusion: SPARK synergizes with physics-based acquisition and reconstruction techniques to improve accelerated MRI by training scan-specific models to estimate and correct reconstruction errors in k-space.
We propose a convolutional neural network (CNN) approach that works synergistically with physics-based reconstruction methods to reduce artifacts in accelerated MRI. Given reconstructed coil k-spaces, our network predicts a k-space correction term for each coil. This is done by matching the difference between the acquired autocalibration lines and their erroneous reconstructions, and generalizing this error term over the entire k-space. Application of this approach on existing reconstruction methods show that SPARK suppresses reconstruction artifacts at high acceleration, while preserving and improving on detail in moderate acceleration rates where existing reconstruction algorithms already perform well; indicating robustness. Introduction Parallel
Cine cardiac magnetic resonance imaging (MRI) is widely used for diagnosis of cardiac diseases thanks to its ability to present cardiovascular features in excellent contrast. As compared to computed tomography (CT), MRI, however, requires a long scan time, which inevitably induces motion artifacts and causes patients discomfort. Thus, there has been a strong clinical motivation to develop techniques to reduce both the scan time and motion artifacts. Given its successful applications in other medical imaging tasks such as MRI super-resolution and CT metal artifact reduction, deep learning is a promising approach for cardiac MRI motion artifact reduction. In this paper, we propose a recurrent neural network to simultaneously extract both spatial and temporal features from under-sampled, motion-blurred cine cardiac images for improved image quality. The experimental results demonstrate substantially improved image quality on two clinical test datasets. Also, our method enables data-driven frame interpolation at an enhanced temporal resolution. Compared with existing methods, our deep learning approach gives a superior performance in terms of structural similarity (SSIM) and peak signal-to-noise ratio (PSNR).
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Deep learning-based image reconstruction methods have achieved promising results across multiple MRI applications. However, most approaches require large-scale fully-sampled ground truth data for supervised training. Acquiring fully-sampled data is often either difficult or impossible, particularly for dynamic contrast enhancement (DCE), 3D cardiac cine, and 4D flow. We present a deep learning framework for MRI reconstruction without any fully-sampled data using generative adversarial networks. We test the proposed method in two scenarios: retrospectively undersampled fast spin echo knee exams and prospectively undersampled abdominal DCE. The method recovers more anatomical structure compared to conventional methods.