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Register a new userReviews: Topological Distances and Losses for Brain Networks
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Added by
Moo K. Chung
Publication date
2021
fields
Informatics Engineering
and research's language is
English
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Almost all statistical and machine learning methods in analyzing brain networks rely on distances and loss functions, which are mostly Euclidean or matrix norms. The Euclidean or matrix distances may fail to capture underlying subtle topological differences in brain networks. Further, Euclidean distances are sensitive to outliers. A few extreme edge weights may severely affect the distance. Thus it is necessary to use distances and loss functions that recognize topology of data. In this review paper, we survey various topological distance and loss functions from topological data analysis (TDA) and persistent homology that can be used in brain network analysis more effectively. Although there are many recent brain imaging studies that are based on TDA methods, possibly due to the lack of method awareness, TDA has not taken as the mainstream tool in brain imaging field yet. The main purpose of this paper is provide the relevant technical survey of these powerful tools that are immediately applicable to brain network data.
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In this article, we show how the recent statistical techniques developed in Topological Data Analysis for the Mapper algorithm can be extended and leveraged to formally define and statistically quantify the presence of topological structures coming from biological phenomena in datasets of CCC contact maps.
Algorithms for persistent homology and zigzag persistent homology are well-studied for persistence modules where homomorphisms are induced by inclusion maps. In this paper, we propose a practical algorithm for computing persistence under $mathbb{Z}_2$ coefficients for a sequence of general simplicial maps and show how these maps arise naturally in some applications of topological data analysis. First, we observe that it is not hard to simulate simplicial maps by inclusion maps but not necessarily in a monotone direction. This, combined with the known algorithms for zigzag persistence, provides an algorithm for computing the persistence induced by simplicial maps. Our main result is that the above simple minded approach can be improved for a sequence of simplicial maps given in a monotone direction. A simplicial map can be decomposed into a set of elementary inclusions and vertex collapses--two atomic operations that can be supported efficiently with the notion of simplex annotations for computing persistent homology. A consistent annotation through these atomic operations implies the maintenance of a consistent cohomology basis, hence a homology basis by duality. While the idea of maintaining a cohomology basis through an inclusion is not new, maintaining them through a vertex collapse is new, which constitutes an important atomic operation for simulating simplicial maps. Annotations support the vertex collapse in addition to the usual inclusion quite naturally. Finally, we exhibit an application of this new tool in which we approximate the persistence diagram of a filtration of Rips complexes where vertex collapses are used to tame the blow-up in size.
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