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Register a new userModel-Based Reinforcement Learning for Type 1Diabetes Blood Glucose Control
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Taku Yamagata
Publication date
2020
fields
Informatics Engineering
and research's language is
English
Authors
Taku Yamagata
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In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels combined with Model Predictive Controller for planning. Echo State Network is a version of recurrent neural networks which allows us to learn long term dependencies in the input of time series data in an online manner. Additionally, we address the quantification of uncertainty for a more robust control. Here, we used ensembles of Echo State Networks to capture model (epistemic) uncertainty. We evaluated the approach with the FDA-approved UVa/Padova Type 1 Diabetes simulator and compared the results against baseline algorithms such as Basal-Bolus controller and Deep Q-learning. The results suggest that the model-based reinforcement learning algorithm can perform equally or better than the baseline algorithms for the majority of virtual Type 1 Diabetes person profiles tested.
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A major challenge in modern reinforcement learning (RL) is efficient control of dynamical systems from high-dimensional sensory observations. Learning controllable embedding (LCE) is a promising approach that addresses this challenge by embedding the observations into a lower-dimensional latent space, estimating the latent dynamics, and utilizing it to perform control in the latent space. Two important questions in this area are how to learn a representation that is amenable to the control problem at hand, and how to achieve an end-to-end framework for representation learning and control. In this paper, we take a few steps towards addressing these questions. We first formulate a LCE model to learn representations that are suitable to be used by a policy iteration style algorithm in the latent space. We call this model control-aware representation learning (CARL). We derive a loss function for CARL that has close connection to the prediction, consistency, and curvature (PCC) principle for representation learning. We derive three implementations of CARL. In the offline implementation, we replace the locally-linear control algorithm (e.g.,~iLQR) used by the existing LCE methods with a RL algorithm, namely model-based soft actor-critic, and show that it results in significant improvement. In online CARL, we interleave representation learning and control, and demonstrate further gain in performance. Finally, we propose value-guided CARL, a variation in which we optimize a weighted version of the CARL loss function, where the weights depend on the TD-error of the current policy. We evaluate the proposed algorithms by extensive experiments on benchmark tasks and compare them with several LCE baselines.
Action delays degrade the performance of reinforcement learning in many real-world systems. This paper proposes a formal definition of delay-aware Markov Decision Process and proves it can be transformed into standard MDP with augmented states using the Markov reward process. We develop a delay-aware model-based reinforcement learning framework that can incorporate the multi-step delay into the learned system models without learning effort. Experiments with the Gym and MuJoCo platforms show that the proposed delay-aware model-based algorithm is more efficient in training and transferable between systems with various durations of delay compared with off-policy model-free reinforcement learning methods. Codes available at: https://github.com/baimingc/dambrl.
Recent breakthroughs in Go play and strategic games have witnessed the great potential of reinforcement learning in intelligently scheduling in uncertain environment, but some bottlenecks are also encountered when we generalize this paradigm to universal complex tasks. Among them, the low efficiency of data utilization in model-free reinforcement algorithms is of great concern. In contrast, the model-based reinforcement learning algorithms can reveal underlying dynamics in learning environments and seldom suffer the data utilization problem. To address the problem, a model-based reinforcement learning algorithm with attention mechanism embedded is proposed as an extension of World Models in this paper. We learn the environment model through Mixture Density Network Recurrent Network(MDN-RNN) for agents to interact, with combinations of variational auto-encoder(VAE) and attention incorporated in state value estimates during the process of learning policy. In this way, agent can learn optimal policies through less interactions with actual environment, and final experiments demonstrate the effectiveness of our model in control problem.
Model-free reinforcement learning (RL) can be used to learn effective policies for complex tasks, such as Atari games, even from image observations. However, this typically requires very large amounts of interaction -- substantially more, in fact, than a human would need to learn the same games. How can people learn so quickly? Part of the answer may be that people can learn how the game works and predict which actions will lead to desirable outcomes. In this paper, we explore how video prediction models can similarly enable agents to solve Atari games with fewer interactions than model-free methods. We describe Simulated Policy Learning (SimPLe), a complete model-based deep RL algorithm based on video prediction models and present a comparison of several model architectures, including a novel architecture that yields the best results in our setting. Our experiments evaluate SimPLe on a range of Atari games in low data regime of 100k interactions between the agent and the environment, which corresponds to two hours of real-time play. In most games SimPLe outperforms state-of-the-art model-free algorithms, in some games by over an order of magnitude.
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