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Register a new userF3RNet: Full-Resolution Residual Registration Network for Deformable Image Registration
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Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream high-to-low, low-to-high network structure, and can achieve satisfactory overall registration results. However, accurate alignments for some severely deformed local regions, which are crucial for pinpointing surgical targets, are often overlooked. Consequently, these approaches are not sensitive to some hard-to-align regions, e.g., intra-patient registration of deformed liver lobes. In this paper, we propose a novel unsupervised registration network, namely the Full-Resolution Residual Registration Network (F3RNet), for deformable registration of severely deformed organs. The proposed method combines two parallel processing streams in a residual learning fashion. One stream takes advantage of the full-resolution information that facilitates accurate voxel-level registration. The other stream learns the deep multi-scale residual representations to obtain robust recognition. We also factorize the 3D convolution to reduce the training parameters and enhance network efficiency. We validate the proposed method on a clinically acquired intra-patient abdominal CT-MRI dataset and a public inspiratory and expiratory thorax CT dataset. Experiments on both multimodal and unimodal registration demonstrate promising results compared to state-of-the-art approaches.
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Human body is a complex dynamic system composed of various sub-dynamic parts. Especially, thoracic and abdominal organs have complex internal shape variations with different frequencies by various reasons such as respiration with fast motion and peristalsis with slower motion. CT protocols for abdominal lesions are multi-phase scans for various tumor detection to use different vascular contrast, however, they are not aligned well enough to visually check the same area. In this paper, we propose a time-efficient and accurate deformable registration algorithm for multi-phase CT scans considering abdominal organ motions, which can be applied for differentiable or non-differentiable motions of abdominal organs. Experimental results shows the registration accuracy as 0.85 +/- 0.45mm (mean +/- STD) for pancreas within 1 minute for the whole abdominal region.
Recently, learning-based algorithms for image inpainting achieve remarkable progress dealing with squared or irregular holes. However, they fail to generate plausible textures inside damaged area because there lacks surrounding information. A progressive inpainting approach would be advantageous for eliminating central blurriness, i.e., restoring well and then updating masks. In this paper, we propose full-resolution residual network (FRRN) to fill irregular holes, which is proved to be effective for progressive image inpainting. We show that well-designed residual architecture facilitates feature integration and texture prediction. Additionally, to guarantee completion quality during progressive inpainting, we adopt N Blocks, One Dilation strategy, which assigns several residual blocks for one dilation step. Correspondingly, a step loss function is applied to improve the performance of intermediate restorations. The experimental results demonstrate that the proposed FRRN framework for image inpainting is much better than previous methods both quantitatively and qualitatively. Our codes are released at: url{https://github.com/ZongyuGuo/Inpainting_FRRN}.
Image registration is a fundamental building block for various applications in medical image analysis. To better explore the correlation between the fixed and moving images and improve registration performance, we propose a novel deep learning network, Co-Attention guided Registration Network (CAR-Net). CAR-Net employs a co-attention block to learn a new representation of the inputs, which drives the registration of the fixed and moving images. Experiments on UK Biobank cardiac cine-magnetic resonance image data demonstrate that CAR-Net obtains higher registration accuracy and smoother deformation fields than state-of-the-art unsupervised registration methods, while achieving comparable or better registration performance than corresponding weakly-supervised variants. In addition, our approach can provide critical structural information of the input fixed and moving images simultaneously in a completely unsupervised manner.
Convolutional neural networks are the most successful models in single image super-resolution. Deeper networks, residual connections, and attention mechanisms have further improved their performance. However, these strategies often improve the reconstruction performance at the expense of considerably increasing the computational cost. This paper introduces a new lightweight super-resolution model based on an efficient method for residual feature and attention aggregation. In order to make an efficient use of the residual features, these are hierarchically aggregated into feature banks for posterior usage at the network output. In parallel, a lightweight hierarchical attention mechanism extracts the most relevant features from the network into attention banks for improving the final output and preventing the information loss through the successive operations inside the network. Therefore, the processing is split into two independent paths of computation that can be simultaneously carried out, resulting in a highly efficient and effective model for reconstructing fine details on high-resolution images from their low-resolution counterparts. Our proposed architecture surpasses state-of-the-art performance in several datasets, while maintaining relatively low computation and memory footprint.
Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration algorithms can still be improved. In this paper, we propose a novel unsupervised learning-based framework to achieve accurate and efficient multi-contrast MR image registrations. Specifically, an end-to-end coarse-to-fine network architecture consisting of affine and deformable transformations is designed to improve the robustness and achieve end-to-end registration. Furthermore, a dual consistency constraint and a new prior knowledge-based loss function are developed to enhance the registration performances. The proposed method has been evaluated on a clinical dataset containing 555 cases, and encouraging performances have been achieved. Compared to the commonly utilized registration methods, including VoxelMorph, SyN, and LT-Net, the proposed method achieves better registration performance with a Dice score of 0.8397 in identifying stroke lesions. With regards to the registration speed, our method is about 10 times faster than the most competitive method of SyN (Affine) when testing on a CPU. Moreover, we prove that our method can still perform well on more challenging tasks with lacking scanning information data, showing high robustness for the clinical application.
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