Recent results from several direct detection experiments have imposed severe constraints on the multi-GeV mass window for various dark matter (DM) models. However, many of these experiments are not sensitive to MeV scale DM as the corresponding recoil energies are, largely, lower than the detector thresholds. We reexamine the light scalar DM in a model-independent approach. In this first of a two-part work, we develop an appropriate methodology to determine the effective coupling of such a DM to hadrons, thereby allowing for the determination of the corresponding annihilation rates. We find that while the parameter space can be constrained using cosmological and astrophysical observations, a significantly large fraction is still viable. In the companion paper, we study the sensitivity of both direct detection experiments as well as colliders to such a DM.