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Register a new userProstate Segmentation using 2D Bridged U-net
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Added by
Yue Zhang
Publication date
2018
fields
Informatics Engineering
and research's language is
English
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In this paper, we focus on three problems in deep learning based medical image segmentation. Firstly, U-net, as a popular model for medical image segmentation, is difficult to train when convolutional layers increase even though a deeper network usually has a better generalization ability because of more learnable parameters. Secondly, the exponential ReLU (ELU), as an alternative of ReLU, is not much different from ReLU when the network of interest gets deep. Thirdly, the Dice loss, as one of the pervasive loss functions for medical image segmentation, is not effective when the prediction is close to ground truth and will cause oscillation during training. To address the aforementioned three problems, we propose and validate a deeper network that can fit medical image datasets that are usually small in the sample size. Meanwhile, we propose a new loss function to accelerate the learning process and a combination of different activation functions to improve the network performance. Our experimental results suggest that our network is comparable or superior to state-of-the-art methods.
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Automatic segmentation of organs-at-risk (OAR) in computed tomography (CT) is an essential part of planning effective treatment strategies to combat lung and esophageal cancer. Accurate segmentation of organs surrounding tumours helps account for the variation in position and morphology inherent across patients, thereby facilitating adaptive and computer-assisted radiotherapy. Although manual delineation of OARs is still highly prevalent, it is prone to errors due to complex variations in the shape and position of organs across patients, and low soft tissue contrast between neighbouring organs in CT images. Recently, deep convolutional neural networks (CNNs) have gained tremendous traction and achieved state-of-the-art results in medical image segmentation. In this paper, we propose a deep learning framework to segment OARs in thoracic CT images, specifically for the: heart, esophagus, trachea and aorta. Our approach employs dilated convolutions and aggregated residual connections in the bottleneck of a U-Net styled network, which incorporates global context and dense information. Our method achieved an overall Dice score of 91.57% on 20 unseen test samples from the ISBI 2019 SegTHOR challenge.
In recent years, computer-aided diagnosis has become an increasingly popular topic. Methods based on convolutional neural networks have achieved good performance in medical image segmentation and classification. Due to the limitations of the convolution operation, the long-term spatial features are often not accurately obtained. Hence, we propose a TransClaw U-Net network structure, which combines the convolution operation with the transformer operation in the encoding part. The convolution part is applied for extracting the shallow spatial features to facilitate the recovery of the image resolution after upsampling. The transformer part is used to encode the patches, and the self-attention mechanism is used to obtain global information between sequences. The decoding part retains the bottom upsampling structure for better detail segmentation performance. The experimental results on Synapse Multi-organ Segmentation Datasets show that the performance of TransClaw U-Net is better than other network structures. The ablation experiments also prove the generalization performance of TransClaw U-Net.
Polyps are the predecessors to colorectal cancer which is considered as one of the leading causes of cancer-related deaths worldwide. Colonoscopy is the standard procedure for the identification, localization, and removal of colorectal polyps. Due to variability in shape, size, and surrounding tissue similarity, colorectal polyps are often missed by the clinicians during colonoscopy. With the use of an automatic, accurate, and fast polyp segmentation method during the colonoscopy, many colorectal polyps can be easily detected and removed. The ``Medico automatic polyp segmentation challenge provides an opportunity to study polyp segmentation and build an efficient and accurate segmentation algorithm. We use the U-Net with pre-trained ResNet50 as the encoder for the polyp segmentation. The model is trained on Kvasir-SEG dataset provided for the challenge and tested on the organizers dataset and achieves a dice coefficient of 0.8154, Jaccard of 0.7396, recall of 0.8533, precision of 0.8532, accuracy of 0.9506, and F2 score of 0.8272, demonstrating the generalization ability of our model.
Multi-instance video object segmentation is to segment specific instances throughout a video sequence in pixel level, given only an annotated first frame. In this paper, we implement an effective fully convolutional networks with U-Net similar structure built on top of OSVOS fine-tuned layer. We use instance isolation to transform this multi-instance segmentation problem into binary labeling problem, and use weighted cross entropy loss and dice coefficient loss as our loss function. Our best model achieves F mean of 0.467 and J mean of 0.424 on DAVIS dataset, which is a comparable performance with the State-of-the-Art approach. But case analysis shows this model can achieve a smoother contour and better instance coverage, meaning it better for recall focused segmentation scenario. We also did experiments on other convolutional neural networks, including Seg-Net, Mask R-CNN, and provide insightful comparison and discussion.
The U-Net was presented in 2015. With its straight-forward and successful architecture it quickly evolved to a commonly used benchmark in medical image segmentation. The adaptation of the U-Net to novel problems, however, comprises several degrees of freedom regarding the exact architecture, preprocessing, training and inference. These choices are not independent of each other and substantially impact the overall performance. The present paper introduces the nnU-Net (no-new-Net), which refers to a robust and self-adapting framework on the basis of 2D and 3D vanilla U-Nets. We argue the strong case for taking away superfluous bells and whistles of many proposed network designs and instead focus on the remaining aspects that make out the performance and generalizability of a method. We evaluate the nnU-Net in the context of the Medical Segmentation Decathlon challenge, which measures segmentation performance in ten disciplines comprising distinct entities, image modalities, image geometries and dataset sizes, with no manual adjustments between datasets allowed. At the time of manuscript submission, nnU-Net achieves the highest mean dice scores across all classes and seven phase 1 tasks (except class 1 in BrainTumour) in the online leaderboard of the challenge.
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