Geographic Information Systems) GIS), and its advanced spatial and statistical analysis of traffic accidents at the city level, play a key role in improving traffic safety and urban development. This paper presents a general methodology for spatial and statistical analysis of traffic accidents within Homs city during three consecutive years 2007, 2008 and 2009. Maps are produced representing the spatial distribution of point traffic accidents within the city where is covered with a network of squares (300 m * 300 m) to identify the most dangerous areas in terms of the number of accidents. A map representing the most dangerous road segments is also produced in Homs city. In addition, the analysis of statistically significant hot spots (Getis-Ord Gi *) is performed. Through this study and the maps produced, dangerous areas and roads segments that have the largest number of accidents during the three years are well identified. These maps can be presented to decision-makers in the field of transport and traffic to study them from all aspects and work to solve the problems that led to an increase in the number of accidents.