The study was done in gyneco-obstetrics department of Tishreen University Hospital at Latakia during 1/1/2018 – 31/12/2018. The number of preterm birth was 160, while the total births was 1520. The percentage of preterm birth was 10,52%. The strongest association was between PTB and PROM, the percentage was 40%. There was important correlation to urinary tract infection, the percentage was 35%. There was important correlation to multiple pregnancy, the percentage was 10,63%. There was correlation to hypertension, with percentage of 14,37%. Precedents of PTB increased the incidence of PTB, the percentage was 26,25%. Smoking has an important role in PTB, the percentage was 31,25%.