We report on the measurements of the total charge changing fragmentation cross sections in high-energy nucleus-nucleus collisions using Fe, Si and Pb incident ions. Several stacks of CR39 nuclear track detectors with different target combinations were exposed at normal incidence to high energy accelerator beams to integrated densities of about 2000 ions/cm^2. The nuclear track detector foils were chemically etched, and ion tracks were measured using an automatic image analyzer system. The cross section determination is based on the charge identification of beam ions and their fragments and on the reconstruction of their path through the stacks.