A procedure has been developed for the charge, mass and energy calibration of ions produced in nuclear heavy ion reactions. The charge and mass identification are based on a $Delta$E-E technique. A computer code determines the conversion from ADC channels into energy values, atomic number and mass of the detected fragments by comparing with energy loss calculations through a minimization routine. The procedure does not need prior measurements with beams of known energy and charge. An application of this technique to the calibration of the MULTICS apparatus is described.