We consider two different constructions of higher brackets. First, based on a Grassmann-odd, nilpotent Delta operator, we define a non-commutative generalization of the higher Koszul brackets, which are used in a generalized Batalin-Vilkovisky algebra, and we show that they form a homotopy Lie algebra. Secondly, we investigate higher, so-called derived brackets built from symmetrized, nested Lie brackets with a fixed nilpotent Lie algebra element Q. We find the most general Jacobi-like identity that such a hierarchy satisfies. The numerical coefficients in front of each term in these generalized Jacobi identities are related to the Bernoulli numbers. We suggest that the definition of a homotopy Lie algebra should be enlarged to accommodate this important case. Finally, we consider the Courant bracket as an example of a derived bracket. We extend it to the big bracket of exterior forms and multi-vectors, and give closed formulas for the higher Courant brackets.