We present comparison of X-ray proxies for the total cluster mass, including the spectral temperature (Tx), gas mass measured within r500 (Mg), and the new proxy, Yx, which is a simple product of Tx and Mg and is related to the total thermal energy of the ICM. We use mock Chandra images constructed for a sample of clusters simulated with the eulerian N-body+gasdynamics adaptive mesh refinement ART code in the concordance LCDM cosmology. The simulations achieve high spatial and mass resolution and include radiative cooling, star formation, and other processes accompanying galaxy formation. Our analysis shows that simulated clusters exhibit a high degree of regularity and tight correlations between the considered observables and total mass. The normalizations of the M-Tx, Mg-Tx, and M-Yx relations agree to better than 10-15% with the current observational measurements of these relations. Our results show that Yx is the best mass proxy with a remarkably low scatter of only ~5-7% in M500 for a fixed Yx, at both low and high redshifts and regardless of whether clusters are relaxed or not. In addition, we show that redshift evolution of the Yx-M500 relation is close to the self-similar prediction, which makes Yx a very attractive mass indicator for measurements of the cluster mass function from X-ray selected samples.
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