We present metallicity estimates for seven open clusters based on spectrophotometric indices from moderate-resolution spectroscopy. Observations of field giants of known metallicity provide a correlation between the spectroscopic indices and the metallicity of open cluster giants. We use chi^2 analysis to fit the relation of spectrophotometric indices to metallicity in field giants. The resulting function allows an estimate of the target-cluster giants metallicities with an error in the method of pm0.08 dex. We derive the following metallicities for the seven open clusters: NGC 1245, [m/H]=-0.14pm0.04; NGC 2099, [m/H]=+0.05pm0.05; NGC 2324, [m/H]=-0.06pm0.04; NGC 2539, [m/H]=-0.04pm0.03; NGC 2682 (M67), [m/H]=-0.05pm0.02; NGC 6705, [m/H]=+0.14pm0.08; NGC 6819, [m/H]=-0.07pm0.12. These metallicity estimates will be useful in planning future extra-solar planet transit searches since planets may form more readily in metal-rich environments.