This paper provides a constructive passivity-based control approach to solve the set-point regulation problem for input-affine continuous nonlinear systems while considering saturation in the inputs. As customarily in passivity-based control, the methodology consists of two steps: energy shaping and damping injection. In terms of applicability, the proposed controllers have two advantages concerning other passivity-based control techniques: (i) the energy shaping is carried out without solving partial differential equations, and (ii) the damping injection is performed without measuring the passive output. The proposed methodology is suitable to control a broad range of physical systems, e.g., mechanical, electrical, and electro-mechanical systems. We illustrate the applicability of the technique by designing controllers for systems in different physical domains, where we validate the analytical results via simulations and experiments.