We provide a comprehensive summary of concepts from Calabi-Yau motives relevant to the computation of multi-loop Feynman integrals. From this we derive several consequences for multi-loop integrals in general, and we illustrate them on the example of multi-loop banana integrals. For example, we show how Griffiths transversality, known from the theory of variation of mixed Hodge structures, leads quite generically to a set of quadratic relations among maximal cut integrals associated to Calabi-Yau motives. These quadratic relations then naturally lead to a compact expression for $l$-loop banana integrals in $D=2$ dimensions in terms of an integral over a period of a Calabi-Yau $(l-1)$-fold. This new integral representation generalizes in a natural way the known representations for $lle 3$ involving logarithms with square root arguments and iterated integrals of Eisenstein series. In a second part, we show how the results obtained by some of the authors in earlier work can be extended to dimensional regularization. We present a method to obtain the differential equations for banana integrals with an arbitrary number of loops in dimensional regularization without the need to solve integration-by-parts relations. We also present a compact formula for the leading asymptotics of banana integrals with an arbitrary number of loops in the large momentum limit. This generalizes the novel $widehat{Gamma}$-class introduced by some of the authors to dimensional regularization and provides a convenient boundary condition to solve the differential equations for the banana integrals. As an application, we present for the first time numerical results for equal-mass banana integrals with up to four loops and up to second order in the dimensional regulator.
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