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An Analysis of Reinforcement Learning for Malaria Control

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 Added by Ndivhuwo Makondo
 Publication date 2021
and research's language is English




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Previous work on policy learning for Malaria control has often formulated the problem as an optimization problem assuming the objective function and the search space have a specific structure. The problem has been formulated as multi-armed bandits, contextual bandits and a Markov Decision Process in isolation. Furthermore, an emphasis is put on developing new algorithms specific to an instance of Malaria control, while ignoring a plethora of simpler and general algorithms in the literature. In this work, we formally study the formulation of Malaria control and present a comprehensive analysis of several formulations used in the literature. In addition, we implement and analyze several reinforcement learning algorithms in all formulations and compare them to black box optimization. In contrast to previous work, our results show that simple algorithms based on Upper Confidence Bounds are sufficient for learning good Malaria policies, and tend to outperform their more advanced counterparts on the malaria OpenAI Gym environment.



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136 - Lixin Zou , Long Xia , Linfang Hou 2021
Sequential decision-making under cost-sensitive tasks is prohibitively daunting, especially for the problem that has a significant impact on peoples daily lives, such as malaria control, treatment recommendation. The main challenge faced by policymakers is to learn a policy from scratch by interacting with a complex environment in a few trials. This work introduces a practical, data-efficient policy learning method, named Variance-Bonus Monte Carlo Tree Search~(VB-MCTS), which can copy with very little data and facilitate learning from scratch in only a few trials. Specifically, the solution is a model-based reinforcement learning method. To avoid model bias, we apply Gaussian Process~(GP) regression to estimate the transitions explicitly. With the GP world model, we propose a variance-bonus reward to measure the uncertainty about the world. Adding the reward to the planning with MCTS can result in more efficient and effective exploration. Furthermore, the derived polynomial sample complexity indicates that VB-MCTS is sample efficient. Finally, outstanding performance on a competitive world-level RL competition and extensive experimental results verify its advantage over the state-of-the-art on the challenging malaria control task.
Reinforcement learning algorithms rely on exploration to discover new behaviors, which is typically achieved by following a stochastic policy. In continuous control tasks, policies with a Gaussian distribution have been widely adopted. Gaussian exploration however does not result in smooth trajectories that generally correspond to safe and rewarding behaviors in practical tasks. In addition, Gaussian policies do not result in an effective exploration of an environment and become increasingly inefficient as the action rate increases. This contributes to a low sample efficiency often observed in learning continuous control tasks. We introduce a family of stationary autoregressive (AR) stochastic processes to facilitate exploration in continuous control domains. We show that proposed processes possess two desirable features: subsequent process observations are temporally coherent with continuously adjustable degree of coherence, and the process stationary distribution is standard normal. We derive an autoregressive policy (ARP) that implements such processes maintaining the standard agent-environment interface. We show how ARPs can be easily used with the existing off-the-shelf learning algorithms. Empirically we demonstrate that using ARPs results in improved exploration and sample efficiency in both simulated and real world domains, and, furthermore, provides smooth exploration trajectories that enable safe operation of robotic hardware.
A major challenge in modern reinforcement learning (RL) is efficient control of dynamical systems from high-dimensional sensory observations. Learning controllable embedding (LCE) is a promising approach that addresses this challenge by embedding the observations into a lower-dimensional latent space, estimating the latent dynamics, and utilizing it to perform control in the latent space. Two important questions in this area are how to learn a representation that is amenable to the control problem at hand, and how to achieve an end-to-end framework for representation learning and control. In this paper, we take a few steps towards addressing these questions. We first formulate a LCE model to learn representations that are suitable to be used by a policy iteration style algorithm in the latent space. We call this model control-aware representation learning (CARL). We derive a loss function for CARL that has close connection to the prediction, consistency, and curvature (PCC) principle for representation learning. We derive three implementations of CARL. In the offline implementation, we replace the locally-linear control algorithm (e.g.,~iLQR) used by the existing LCE methods with a RL algorithm, namely model-based soft actor-critic, and show that it results in significant improvement. In online CARL, we interleave representation learning and control, and demonstrate further gain in performance. Finally, we propose value-guided CARL, a variation in which we optimize a weighted version of the CARL loss function, where the weights depend on the TD-error of the current policy. We evaluate the proposed algorithms by extensive experiments on benchmark tasks and compare them with several LCE baselines.
We provide a framework for incorporating robustness -- to perturbations in the transition dynamics which we refer to as model misspecification -- into continuous control Reinforcement Learning (RL) algorithms. We specifically focus on incorporating robustness into a state-of-the-art continuous control RL algorithm called Maximum a-posteriori Policy Optimization (MPO). We achieve this by learning a policy that optimizes for a worst case expected return objective and derive a corresponding robust entropy-regularized Bellman contraction operator. In addition, we introduce a less conservative, soft-robust, entropy-regularized objective with a corresponding Bellman operator. We show that both, robust and soft-robust policies, outperform their non-robust counterparts in nine Mujoco domains with environment perturbations. In addition, we show improved robust performance on a high-dimensional, simulated, dexterous robotic hand. Finally, we present multiple investigative experiments that provide a deeper insight into the robustness framework. This includes an adaptation to another continuous control RL algorithm as well as learning the uncertainty set from offline data. Performance videos can be found online at https://sites.google.com/view/robust-rl.
Continuous control tasks in reinforcement learning are important because they provide an important framework for learning in high-dimensional state spaces with deceptive rewards, where the agent can easily become trapped into suboptimal solutions. One way to avoid local optima is to use a population of agents to ensure coverage of the policy space, yet learning a population with the best coverage is still an open problem. In this work, we present a novel approach to population-based RL in continuous control that leverages properties of normalizing flows to perform attractive and repulsive operations between current members of the population and previously observed policies. Empirical results on the MuJoCo suite demonstrate a high performance gain for our algorithm compared to prior work, including Soft-Actor Critic (SAC).

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