Filtration of feed containing multiple species of particles is a common process in the industrial setting. In this work we propose a model for filtration of a suspension containing an arbitrary number of particle species, each with different affinities for the filter membrane. We formulate a number of optimization problems pertaining to effective separation of desired and undesired particles in the special case of two particle species and we present results showing how properties such as feed composition affect the optimal filter design (internal pore structure). In addition, we propose a novel multi-stage filtration strategy, which provides a significant mass yield improvement for the desired particles, and, surprisingly, higher purity of the product as well.
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