Irreversibility is usually captured by a comparison between the process that happens and a corresponding reverse process. In the last decades, this comparison has been extensively studied through fluctuation relations. Here we revisit fluctuation relations from the standpoint, suggested decades ago by Watanabe, that the comparison should involve the prediction and the retrodiction on the unique process, rather than two processes. We identify a necessary and sufficient condition for a retrodictive reading of a fluctuation relation. The retrodictive narrative also brings to the fore the possibility of deriving fluctuation relations based on various statistical divergences, and clarifies some of the traditional assumptions as arising from the choice of a reference prior.