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Training like Playing: A Reinforcement Learning And Knowledge Graph-based framework for building Automatic Consultation System in Medical Field

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 Added by Yining Huang
 Publication date 2021
and research's language is English




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We introduce a framework for AI-based medical consultation system with knowledge graph embedding and reinforcement learning components and its implement. Our implement of this framework leverages knowledge organized as a graph to have diagnosis according to evidence collected from patients recurrently and dynamically. According to experiment we designed for evaluating its performance, it archives a good result. More importantly, for getting better performance, researchers can implement it on this framework based on their innovative ideas, well designed experiments and even clinical trials.



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Developing conversational agents to interact with patients and provide primary clinical advice has attracted increasing attention due to its huge application potential, especially in the time of COVID-19 Pandemic. However, the training of end-to-end neural-based medical dialogue system is restricted by an insufficient quantity of medical dialogue corpus. In this work, we make the first attempt to build and release a large-scale high-quality Medical Dialogue dataset related to 12 types of common Gastrointestinal diseases named MedDG, with more than 17K conversations collected from the online health consultation community. Five different categories of entities, including diseases, symptoms, attributes, tests, and medicines, are annotated in each conversation of MedDG as additional labels. To push forward the future research on building expert-sensitive medical dialogue system, we proposes two kinds of medical dialogue tasks based on MedDG dataset. One is the next entity prediction and the other is the doctor response generation. To acquire a clear comprehension on these two medical dialogue tasks, we implement several state-of-the-art benchmarks, as well as design two dialogue models with a further consideration on the predicted entities. Experimental results show that the pre-train language models and other baselines struggle on both tasks with poor performance in our dataset, and the response quality can be enhanced with the help of auxiliary entity information. From human evaluation, the simple retrieval model outperforms several state-of-the-art generative models, indicating that there still remains a large room for improvement on generating medically meaningful responses.
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Supervised deep learning has achieved remarkable success in various applications. Successful machine learning application however depends on the availability of sufficiently large amount of data. In the absence of data from the target domain, representative data collection from multiple sources is often needed. However, a model trained on existing multi-source data might generalize poorly on the unseen target domain. This problem is referred to as domain shift. In this paper, we explore the suitability of multi-source training data selection to tackle the domain shift challenge in the context of domain generalization. We also propose a microservice-oriented methodology for supporting this solution. We perform our experimental study on the use case of building energy consumption prediction. Experimental results suggest that minimal building description is capable of improving cross-building generalization performances when used to select energy consumption data.
While the demand for machine learning (ML) applications is booming, there is a scarcity of data scientists capable of building such models. Automatic machine learning (AutoML) approaches have been proposed that help with this problem by synthesizing end-to-end ML data processing pipelines. However, these follow a best-effort approach and a user in the loop is necessary to curate and refine the derived pipelines. Since domain experts often have little or no expertise in machine learning, easy-to-use interactive interfaces that guide them throughout the model building process are necessary. In this paper, we present Visus, a system designed to support the model building process and curation of ML data processing pipelines generated by AutoML systems. We describe the framework used to ground our design choices and a usage scenario enabled by Visus. Finally, we discuss the feedback received in user testing sessions with domain experts.
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In recent years deep neural networks have been successfully applied to the domains of reinforcement learning cite{bengio2009learning,krizhevsky2012imagenet,hinton2006reducing}. Deep reinforcement learning cite{mnih2015human} is reported to have the advantage of learning effective policies directly from high-dimensional sensory inputs over traditional agents. However, within the scope of the literature, there is no fundamental change or improvement on the existing training framework. Here we propose a novel training framework that is conceptually comprehensible and potentially easy to be generalized to all feasible algorithms for reinforcement learning. We employ Monte-carlo sampling to achieve raw data inputs, and train them in batch to achieve Markov decision process sequences and synchronously update the network parameters instead of experience replay. This training framework proves to optimize the unbiased approximation of loss function whose estimation exactly matches the real probability distribution data inputs follow, and thus have overwhelming advantages of sample efficiency and convergence rate over existing deep reinforcement learning after evaluating it on both discrete action spaces and continuous control problems. Besides, we propose several algorithms embedded with our new framework to deal with typical discrete and continuous scenarios. These algorithms prove to be far more efficient than their origin
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