No Arabic abstract
Low-electron-dose observation is indispensable for observing various samples using a transmission electron microscope; consequently, image processing has been used to improve transmission electron microscopy (TEM) images. To apply such image processing to in situ observations, we here apply a convolutional neural network to TEM imaging. Using a dataset that includes short-exposure images and long-exposure images, we develop a pipeline for processed short-exposure images, based on end-to-end training. The quality of images acquired with a total dose of approximately 5 e- per pixel becomes comparable to that of images acquired with a total dose of approximately 1000 e- per pixel. Because the conversion time is approximately 8 ms, in situ observation at 125 fps is possible. This imaging technique enables in situ observation of electron-beam-sensitive specimens.
Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments. Proposed strategies for eliminating beam damage also decrease reconstruction quality. Here we present a deep learning-based method to enhance low-dose tomography reconstruction via a hybrid-dose acquisition strategy composed of extremely sparse-view normal-dose projections and full-view low-dose projections. Corresponding image pairs are extracted from low-/normal-dose projections to train a deep convolutional neural network, which is then applied to enhance full-view noisy low-dose projections. Evaluation on two experimental datasets under different hybrid-dose acquisition conditions show significantly improved structural details and reduced noise levels compared to uniformly distributed acquisitions with the same number of total dosage. The resulting reconstructions also preserve more structural information than reconstructions processed with traditional analytical and regularization-based iterative reconstruction methods from uniform acquisitions. Our performance comparisons show that our implementation, HDrec, can perform denoising of a real-world experimental data 410x faster than the state-of-the-art Xlearn method while providing better quality. This framework can be applied to other tomographic or scanning based X-ray imaging techniques for enhanced analysis of dose-sensitive samples and has great potential for studying fast dynamic processes.
The extensive use of medical CT has raised a public concern over the radiation dose to the patient. Reducing the radiation dose leads to increased CT image noise and artifacts, which can adversely affect not only the radiologists judgement but also the performance of downstream medical image analysis tasks. Various low-dose CT denoising methods, especially the recent deep learning based approaches, have produced impressive results. However, the existing denoising methods are all downstream-task-agnostic and neglect the diverse needs of the downstream applications. In this paper, we introduce a novel Task-Oriented Denoising Network (TOD-Net) with a task-oriented loss leveraging knowledge from the downstream tasks. Comprehensive empirical analysis shows that the task-oriented loss complements other task agnostic losses by steering the denoiser to enhance the image quality in the task related regions of interest. Such enhancement in turn brings general boosts on the performance of various methods for the downstream task. The presented work may shed light on the future development of context-aware image denoising methods.
Images obtained in real-world low-light conditions are not only low in brightness, but they also suffer from many other types of degradation, such as color bias, unknown noise, detail loss and halo artifacts. In this paper, we propose a very fast deep learning framework called Bringing the Lightness (denoted as BLNet) that consists of two U-Nets with a series of well-designed loss functions to tackle all of the above degradations. Based on Retinex Theory, the decomposition net in our model can decompose low-light images into reflectance and illumination and remove noise in the reflectance during the decomposition phase. We propose a Noise and Color Bias Control module (NCBC Module) that contains a convolutional neural network and two loss functions (noise loss and color loss). This module is only used to calculate the loss functions during the training phase, so our method is very fast during the test phase. This module can smooth the reflectance to achieve the purpose of noise removal while preserving details and edge information and controlling color bias. We propose a network that can be trained to learn the mapping between low-light and normal-light illumination and enhance the brightness of images taken in low-light illumination. We train and evaluate the performance of our proposed model over the real-world Low-Light (LOL) dataset), and we also test our model over several other frequently used datasets (LIME, DICM and MEF datasets). We conduct extensive experiments to demonstrate that our approach achieves a promising effect with good rubustness and generalization and outperforms many other state-of-the-art methods qualitatively and quantitatively. Our method achieves high speed because we use loss functions instead of introducing additional denoisers for noise removal and color correction. The code and model are available at https://github.com/weixinxu666/BLNet.
Cancer patients have a higher risk of cardiovascular disease (CVD) mortality than the general population. Low dose computed tomography (LDCT) for lung cancer screening offers an opportunity for simultaneous CVD risk estimation in at-risk patients. Our deep learning CVD risk prediction model, trained with 30,286 LDCTs from the National Lung Cancer Screening Trial, achieved an area under the curve (AUC) of 0.871 on a separate test set of 2,085 subjects and identified patients with high CVD mortality risks (AUC of 0.768). We validated our model against ECG-gated cardiac CT based markers, including coronary artery calcification (CAC) score, CAD-RADS score, and MESA 10-year risk score from an independent dataset of 335 subjects. Our work shows that, in high-risk patients, deep learning can convert LDCT for lung cancer screening into a dual-screening quantitative tool for CVD risk estimation.
Image denoising is one of the most critical problems in mobile photo processing. While many solutions have been proposed for this task, they are usually working with synthetic data and are too computationally expensive to run on mobile devices. To address this problem, we introduce the first Mobile AI challenge, where the target is to develop an end-to-end deep learning-based image denoising solution that can demonstrate high efficiency on smartphone GPUs. For this, the participants were provided with a novel large-scale dataset consisting of noisy-clean image pairs captured in the wild. The runtime of all models was evaluated on the Samsung Exynos 2100 chipset with a powerful Mali GPU capable of accelerating floating-point and quantized neural networks. The proposed solutions are fully compatible with any mobile GPU and are capable of processing 480p resolution images under 40-80 ms while achieving high fidelity results. A detailed description of all models developed in the challenge is provided in this paper.