A grand challenge in fundamental physics and practical applications is overcoming wave diffusion to deposit energy into a target region deep inside a diffusive system. While it is known that coherently controlling the incident wavefront allows diffraction-limited focusing inside a diffusive system, in many applications targets are significantly larger than such a focus and the maximum deliverable energy remains unknown. Here, we introduce the deposition matrix, which maps an input wavefront to its internal field distribution, and theoretically predict the ultimate limitations on energy deposition at any depth. For example, the maximum obtainable energy enhancement occurs at 3/4 a diffusive systems thickness: regardless of its scattering strength. Experimentally we measure the deposition matrix and excite its eigenstates to enhance/suppress the energy within an extended target region. Our theoretical analysis reveals that such enhancement/suppression results from both selective transmission eigenchannel excitation and constructive/destructive interference among these channels.
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