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Register a new userOut-of-Distribution Detection in Dermatology using Input Perturbation and Subset Scanning
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Added by
Celia Cintas
Publication date
2021
fields
Informatics Engineering
and research's language is
English
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Recent advances in deep learning have led to breakthroughs in the development of automated skin disease classification. As we observe an increasing interest in these models in the dermatology space, it is crucial to address aspects such as the robustness towards input data distribution shifts. Current skin disease models could make incorrect inferences for test samples from different hardware devices and clinical settings or unknown disease samples, which are out-of-distribution (OOD) from the training samples. To this end, we propose a simple yet effective approach that detect these OOD samples prior to making any decision. The detection is performed via scanning in the latent space representation (e.g., activations of the inner layers of any pre-trained skin disease classifier). The input samples could also perturbed to maximise divergence of OOD samples. We validate our ODD detection approach in two use cases: 1) identify samples collected from different protocols, and 2) detect samples from unknown disease classes. Additionally, we evaluate the performance of the proposed approach and compare it with other state-of-the-art methods. Furthermore, data-driven dermatology applications may deepen the disparity in clinical care across racial and ethnic groups since most datasets are reported to suffer from bias in skin tone distribution. Therefore, we also evaluate the fairness of these OOD detection methods across different skin tones. Our experiments resulted in competitive performance across multiple datasets in detecting OOD samples, which could be used (in the future) to design more effective transfer learning techniques prior to inferring on these samples.
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Identifying anomalous patterns in real-world data is essential for understanding where, when, and how systems deviate from their expected dynamics. Yet methods that separately consider the anomalousness of each individual data point have low detection power for subtle, emerging irregularities. Additionally, recent detection techniques based on subset scanning make strong independence assumptions and suffer degraded performance in correlated data. We introduce methods for identifying anomalous patterns in non-iid data by combining Gaussian processes with novel log-likelihood ratio statistic and subset scanning techniques. Our approaches are powerful, interpretable, and can integrate information across multiple data streams. We illustrate their performance on numeric simulations and three open source spatiotemporal datasets of opioid overdose deaths, 311 calls, and storm reports.
Detecting out-of-distribution (OOD) inputs is a central challenge for safely deploying machine learning models in the real world. Existing solutions are mainly driven by small datasets, with low resolution and very few class labels (e.g., CIFAR). As a result, OOD detection for large-scale image classification tasks remains largely unexplored. In this paper, we bridge this critical gap by proposing a group-based OOD detection framework, along with a novel OOD scoring function termed MOS. Our key idea is to decompose the large semantic space into smaller groups with similar concepts, which allows simplifying the decision boundaries between in- vs. out-of-distribution data for effective OOD detection. Our method scales substantially better for high-dimensional class space than previous approaches. We evaluate models trained on ImageNet against four carefully curated OOD datasets, spanning diverse semantics. MOS establishes state-of-the-art performance, reducing the average FPR95 by 14.33% while achieving 6x speedup in inference compared to the previous best method.
Current out-of-distribution (OOD) detection benchmarks are commonly built by defining one dataset as in-distribution (ID) and all others as OOD. However, these benchmarks unfortunately introduce some unwanted and impractical goals, e.g., to perfectly distinguish CIFAR dogs from ImageNet dogs, even though they have the same semantics and negligible covariate shifts. These unrealistic goals will result in an extremely narrow range of model capabilities, greatly limiting their use in real applications. To overcome these drawbacks, we re-design the benchmarks and propose the semantically coherent out-of-distribution detection (SC-OOD). On the SC-OOD benchmarks, existing methods suffer from large performance degradation, suggesting that they are extremely sensitive to low-level discrepancy between data sources while ignoring their inherent semantics. To develop an effective SC-OOD detection approach, we leverage an external unlabeled set and design a concise framework featured by unsupervised dual grouping (UDG) for the joint modeling of ID and OOD data. The proposed UDG can not only enrich the semantic knowledge of the model by exploiting unlabeled data in an unsupervised manner, but also distinguish ID/OOD samples to enhance ID classification and OOD detection tasks simultaneously. Extensive experiments demonstrate that our approach achieves state-of-the-art performance on SC-OOD benchmarks. Code and benchmarks are provided on our project page: https://jingkang50.github.io/projects/scood.
Out-of-Distribution (OoD) detection is important for building safe artificial intelligence systems. However, current OoD detection methods still cannot meet the performance requirements for practical deployment. In this paper, we propose a simple yet effective algorithm based on a novel observation: in a trained neural network, OoD samples with bounded norms well concentrate in the feature space. We call the center of OoD features the Feature Space Singularity (FSS), and denote the distance of a sample feature to FSS as FSSD. Then, OoD samples can be identified by taking a threshold on the FSSD. Our analysis of the phenomenon reveals why our algorithm works. We demonstrate that our algorithm achieves state-of-the-art performance on various OoD detection benchmarks. Besides, FSSD also enjoys robustness to slight corruption in test data and can be further enhanced by ensembling. These make FSSD a promising algorithm to be employed in real world. We release our code at url{https://github.com/megvii-research/FSSD_OoD_Detection}.
Image classification models deployed in the real world may receive inputs outside the intended data distribution. For critical applications such as clinical decision making, it is important that a model can detect such out-of-distribution (OOD) inputs and express its uncertainty. In this work, we assess the capability of various state-of-the-art approaches for confidence-based OOD detection through a comparative study and in-depth analysis. First, we leverage a computer vision benchmark to reproduce and compare multiple OOD detection methods. We then evaluate their capabilities on the challenging task of disease classification using chest X-rays. Our study shows that high performance in a computer vision task does not directly translate to accuracy in a medical imaging task. We analyse factors that affect performance of the methods between the two tasks. Our results provide useful insights for developing the next generation of OOD detection methods.
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