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MIASSR: An Approach for Medical Image Arbitrary Scale Super-Resolution

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 Added by Jin Zhu
 Publication date 2021
and research's language is English




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Single image super-resolution (SISR) aims to obtain a high-resolution output from one low-resolution image. Currently, deep learning-based SISR approaches have been widely discussed in medical image processing, because of their potential to achieve high-quality, high spatial resolution images without the cost of additional scans. However, most existing methods are designed for scale-specific SR tasks and are unable to generalise over magnification scales. In this paper, we propose an approach for medical image arbitrary-scale super-resolution (MIASSR), in which we couple meta-learning with generative adversarial networks (GANs) to super-resolve medical images at any scale of magnification in (1, 4]. Compared to state-of-the-art SISR algorithms on single-modal magnetic resonance (MR) brain images (OASIS-brains) and multi-modal MR brain images (BraTS), MIASSR achieves comparable fidelity performance and the best perceptual quality with the smallest model size. We also employ transfer learning to enable MIASSR to tackle SR tasks of new medical modalities, such as cardiac MR images (ACDC) and chest computed tomography images (COVID-CT). The source code of our work is also public. Thus, MIASSR has the potential to become a new foundational pre-/post-processing step in clinical image analysis tasks such as reconstruction, image quality enhancement, and segmentation.



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We describe our solution for the PIRM Super-Resolution Challenge 2018 where we achieved the 2nd best perceptual quality for average RMSE<=16, 5th best for RMSE<=12.5, and 7th best for RMSE<=11.5. We modify a recently proposed Multi-Grid Back-Projection (MGBP) architecture to work as a generative system with an input parameter that can control the amount of artificial details in the output. We propose a discriminator for adversarial training with the following novel properties: it is multi-scale that resembles a progressive-GAN; it is recursive that balances the architecture of the generator; and it includes a new layer to capture significant statistics of natural images. Finally, we propose a training strategy that avoids conflicts between reconstruction and perceptual losses. Our configuration uses only 281k parameters and upscales each image of the competition in 0.2s in average.
Recently, the single image super-resolution (SISR) approaches with deep and complex convolutional neural network structures have achieved promising performance. However, those methods improve the performance at the cost of higher memory consumption, which is difficult to be applied for some mobile devices with limited storage and computing resources. To solve this problem, we present a lightweight multi-scale feature interaction network (MSFIN). For lightweight SISR, MSFIN expands the receptive field and adequately exploits the informative features of the low-resolution observed images from various scales and interactive connections. In addition, we design a lightweight recurrent residual channel attention block (RRCAB) so that the network can benefit from the channel attention mechanism while being sufficiently lightweight. Extensive experiments on some benchmarks have confirmed that our proposed MSFIN can achieve comparable performance against the state-of-the-arts with a more lightweight model.
We introduce a simple and efficient lossless image compression algorithm. We store a low resolution version of an image as raw pixels, followed by several iterations of lossless super-resolution. For lossless super-resolution, we predict the probability of a high-resolution image, conditioned on the low-resolution input, and use entropy coding to compress this super-resolution operator. Super-Resolution based Compression (SReC) is able to achieve state-of-the-art compression rates with practical runtimes on large datasets. Code is available online at https://github.com/caoscott/SReC.
We present SR3, an approach to image Super-Resolution via Repeated Refinement. SR3 adapts denoising diffusion probabilistic models to conditional image generation and performs super-resolution through a stochastic denoising process. Inference starts with pure Gaussian noise and iteratively refines the noisy output using a U-Net model trained on denoising at various noise levels. SR3 exhibits strong performance on super-resolution tasks at different magnification factors, on faces and natural images. We conduct human evaluation on a standard 8X face super-resolution task on CelebA-HQ, comparing with SOTA GAN methods. SR3 achieves a fool rate close to 50%, suggesting photo-realistic outputs, while GANs do not exceed a fool rate of 34%. We further show the effectiveness of SR3 in cascaded image generation, where generative models are chained with super-resolution models, yielding a competitive FID score of 11.3 on ImageNet.
319 - Luke Oakden-Rayner 2019
Rationale and Objectives: Medical artificial intelligence systems are dependent on well characterised large scale datasets. Recently released public datasets have been of great interest to the field, but pose specific challenges due to the disconnect they cause between data generation and data usage, potentially limiting the utility of these datasets. Materials and Methods: We visually explore two large public datasets, to determine how accurate the provided labels are and whether other subtle problems exist. The ChestXray14 dataset contains 112,120 frontal chest films, and the MURA dataset contains 40,561 upper limb radiographs. A subset of around 700 images from both datasets was reviewed by a board-certified radiologist, and the quality of the original labels was determined. Results: The ChestXray14 labels did not accurately reflect the visual content of the images, with positive predictive values mostly between 10% and 30% lower than the values presented in the original documentation. There were other significant problems, with examples of hidden stratification and label disambiguation failure. The MURA labels were more accurate, but the original normal/abnormal labels were inaccurate for the subset of cases with degenerative joint disease, with a sensitivity of 60% and a specificity of 82%. Conclusion: Visual inspection of images is a necessary component of understanding large image datasets. We recommend that teams producing public datasets should perform this important quality control procedure and include a thorough description of their findings, along with an explanation of the data generating procedures and labelling rules, in the documentation for their datasets.
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