We approach the quasi-isometric classification questions on Lie groups by considering low dimensional cases and isometries alongside quasi-isometries. First, we present some new results related to quasi-isometries between Heintze groups. Then we will see how these results together with the existing tools related to isometries can be applied to groups of dimension 4 and 5 in particular. Thus we take steps towards determining all the equivalence classes of groups up to isometry and quasi-isometry. We completely solve the classification up to isometry for simply connected solvable groups in dimension 4, and for the subclass of groups of polynomial growth in dimension 5.