Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userMultitasking Deep Learning Model for Detection of Five Stages of Diabetic Retinopathy
224
0
0.0
(
0
)
Ask ChatGPT about the research
No Arabic abstract
This paper presents a multitask deep learning model to detect all the five stages of diabetic retinopathy (DR) consisting of no DR, mild DR, moderate DR, severe DR, and proliferate DR. This multitask model consists of one classification model and one regression model, each with its own loss function. Noting that a higher severity level normally occurs after a lower severity level, this dependency is taken into consideration by concatenating the classification and regression models. The regression model learns the inter-dependency between the stages and outputs a score corresponding to the severity level of DR generating a higher score for a higher severity level. After training the regression model and the classification model separately, the features extracted by these two models are concatenated and inputted to a multilayer perceptron network to classify the five stages of DR. A modified Squeeze Excitation Densely Connected deep neural network is developed to implement this multitasking approach. The developed multitask model is then used to detect the five stages of DR by examining the two large Kaggle datasets of APTOS and EyePACS. A multitasking transfer learning model based on Xception network is also developed to evaluate the proposed approach by classifying DR into five stages. It is found that the developed model achieves a weighted Kappa score of 0.90 and 0.88 for the APTOS and EyePACS datasets, respectively, higher than any existing methods for detection of the five stages of DR
rate research
Read More
Diabetic retinopathy (DR) screening is instrumental in preventing blindness, but faces a scaling challenge as the number of diabetic patients rises. Risk stratification for the development of DR may help optimize screening intervals to reduce costs while improving vision-related outcomes. We created and validated t
Though deep learning has shown successful performance in classifying the label and severity stage of certain diseases, most of them give few explanations on how to make predictions. Inspired by Kochs Postulates, the foundation in evidence-based medicine (EBM) to identify the pathogen, we propose to exploit the interpretability of deep learning application in medical diagnosis. By determining and isolating the neuron activation patterns on which diabetic retinopathy (DR) detector relies to make decisions, we demonstrate the direct relation between the isolated neuron activation and lesions for a pathological explanation. To be specific, we first define novel pathological descriptors using activated neurons of the DR detector to encode both spatial and appearance information of lesions. Then, to visualize the symptom encoded in the descriptor, we propose Patho-GAN, a new network to synthesize medically plausible retinal images. By manipulating these descriptors, we could even arbitrarily control the position, quantity, and categories of generated lesions. We also show that our synthesized images carry the symptoms directly related to diabetic retinopathy diagnosis. Our generated images are both qualitatively and quantitatively superior to the ones by previous methods. Besides, compared to existing methods that take hours to generate an image, our second level speed endows the potential to be an effective solution for data augmentation.
Diabetes is one of the most prevalent chronic diseases in Bangladesh, and as a result, Diabetic Retinopathy (DR) is widespread in the population. DR, an eye illness caused by diabetes, can lead to blindness if it is not identified and treated in its early stages. Unfortunately, diagnosis of DR requires medically trained professionals, but Bangladesh has limited specialists in comparison to its population. Moreover, the screening process is often expensive, prohibiting many from receiving timely and proper diagnosis. To address the problem, we introduce a deep learning algorithm which screens for different stages of DR. We use a state-of-the-art CNN architecture to diagnose patients based on retinal fundus imagery. This paper is an experimental evaluation of the algorithm we developed for DR diagnosis and screening specifically for Bangladeshi patients. We perform this validation study using separate pools of retinal image data of real patients from a hospital and field studies in Bangladesh. Our results show that the algorithm is effective at screening Bangladeshi eyes even when trained on a public dataset which is out of domain, and can accurately determine the stage of DR as well, achieving an overall accuracy of 92.27% and 93.02% on two validation sets of Bangladeshi eyes. The results confirm the ability of the algorithm to be used in real clinical settings and applications due to its high accuracy and classwise metrics. Our algorithm is implemented in the application Drishti, which is used to screen for DR in patients living in rural areas in Bangladesh, where access to professional screening is limited.
Diabetes foot ulceration (DFU) and amputation are a cause of significant morbidity. The prevention of DFU may be achieved by the identification of patients at risk of DFU and the institution of preventative measures through education and offloading. Several studies have reported that thermogram images may help to detect an increase in plantar temperature prior to DFU. However, the distribution of plantar temperature may be heterogeneous, making it difficult to quantify and utilize to predict outcomes. We have compared a machine learning-based scoring technique with feature selection and optimization techniques and learning classifiers to several state-of-the-art Convolutional Neural Networks (CNNs) on foot thermogram images and propose a robust solution to identify the diabetic foot. A comparatively shallow CNN model, MobilenetV2 achieved an F1 score of ~95% for a two-feet thermogram image-based classification and the AdaBoost Classifier used 10 features and achieved an F1 score of 97 %. A comparison of the inference time for the best-performing networks confirmed that the proposed algorithm can be deployed as a smartphone application to allow the user to monitor the progression of the DFU in a home setting.
DRDr II is a hybrid of machine learning and deep learning worlds. It builds on the successes of its antecedent, namely, DRDr, that was trained to detect, locate, and create segmentation masks for two types of lesions (exudates and microaneurysms) that can be found in the eyes of the Diabetic Retinopathy (DR) patients; and uses the entire model as a solid feature extractor in the core of its pipeline to detect the severity level of the DR cases. We employ a big dataset with over 35 thousand fundus images collected from around the globe and after 2 phases of preprocessing alongside feature extraction, we succeed in predicting the correct severity levels with over 92% accuracy.
suggested questions
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
