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Register a new userBayesian Bootstrap Spike-and-Slab LASSO
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Lizhen Nie
Publication date
2020
fields
Mathematical Statistics
and research's language is
English
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The impracticality of posterior sampling has prevented the widespread adoption of spike-and-slab priors in high-dimensional applications. To alleviate the computational burden, optimization strategies have been proposed that quickly find local posterior modes. Trading off uncertainty quantification for computational speed, these strategies have enabled spike-and-slab deployments at scales that would be previously unfeasible. We build on one recent development in this strand of work: the Spike-and-Slab LASSO procedure of Rov{c}kov{a} and George (2018). Instead of optimization, however, we explore multiple avenues for posterior sampling, some traditional and some new. Intrigued by the speed of Spike-and-Slab LASSO mode detection, we explore the possibility of sampling from an approximate posterior by performing MAP optimization on many independently perturbed datasets. To this end, we explore Bayesian bootstrap ideas and introduce a new class of jittered Spike-and-Slab LASSO priors with random shrinkage targets. These priors are a key constituent of the Bayesian Bootstrap Spike-and-Slab LASSO (BB-SSL) method proposed here. BB-SSL turns fast optimization into approximate posterior sampling. Beyond its scalability, we show that BB-SSL has a strong theoretical support. Indeed, we find that the induced pseudo-posteriors contract around the truth at a near-optimal rate in sparse normal-means and in high-dimensional regression. We compare our algorithm to the traditional Stochastic Search Variable Selection (under Laplace priors) as well as many state-of-the-art methods for shrinkage priors. We show, both in simulations and on real data, that our method fares superbly in these comparisons, often providing substantial computational gains.
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High-dimensional data sets have become ubiquitous in the past few decades, often with many more covariates than observations. In the frequentist setting, penalized likelihood methods are the most popular approach for variable selection and estimation in high-dimensional data. In the Bayesian framework, spike-and-slab methods are commonly used as probabilistic constructs for high-dimensional modeling. Within the context of linear regression, Rockova and George (2018) introduced the spike-and-slab LASSO (SSL), an approach based on a prior which provides a continuum between the penalized likelihood LASSO and the Bayesian point-mass spike-and-slab formulations. Since its inception, the spike-and-slab LASSO has been extended to a variety of contexts, including generalized linear models, factor analysis, graphical models, and nonparametric regression. The goal of this paper is to survey the landscape surrounding spike-and-slab LASSO methodology. First we elucidate the attractive properties and the computational tractability of SSL priors in high dimensions. We then review methodological developments of the SSL and outline several theoretical developments. We illustrate the methodology on both simulated and real datasets.
Sparse principal component analysis (PCA) is a popular tool for dimensional reduction of high-dimensional data. Despite its massive popularity, there is still a lack of theoretically justifiable Bayesian sparse PCA that is computationally scalable. A major challenge is choosing a suitable prior for the loadings matrix, as principal components are mutually orthogonal. We propose a spike and slab prior that meets this orthogonality constraint and show that the posterior enjoys both theoretical and computational advantages. Two computational algorithms, the PX-CAVI and the PX-EM algorithms, are developed. Both algorithms use parameter expansion to deal with the orthogonality constraint and to accelerate their convergence speeds. We found that the PX-CAVI algorithm has superior empirical performance than the PX-EM algorithm and two other penalty methods for sparse PCA. The PX-CAVI algorithm is then applied to study a lung cancer gene expression dataset. $mathsf{R}$ package $mathsf{VBsparsePCA}$ with an implementation of the algorithm is available on The Comprehensive R Archive Network.
We propose a Bayesian procedure for simultaneous variable and covariance selection using continuous spike-and-slab priors in multivariate linear regression models where q possibly correlated responses are regressed onto p predictors. Rather than relying on a stochastic search through the high-dimensional model space, we develop an ECM algorithm similar to the EMVS procedure of Rockova & George (2014) targeting modal estimates of the matrix of regression coefficients and residual precision matrix. Varying the scale of the continuous spike densities facilitates dynamic posterior exploration and allows us to filter out negligible regression coefficients and partial covariances gradually. Our method is seen to substantially outperform regularization competitors on simulated data. We demonstrate our method with a re-examination of data from a recent observational study of the effect of playing high school football on several later-life cognition, psychological, and socio-economic outcomes.
An important task in building regression models is to decide which regressors should be included in the final model. In a Bayesian approach, variable selection can be performed using mixture priors with a spike and a slab component for the effects subject to selection. As the spike is concentrated at zero, variable selection is based on the probability of assigning the corresponding regression effect to the slab component. These posterior inclusion probabilities can be determined by MCMC sampling. In this paper we compare the MCMC implementations for several spike and slab priors with regard to posterior inclusion probabilities and their sampling efficiency for simulated data. Further, we investigate posterior inclusion probabilities analytically for different slabs in two simple settings. Application of variable selection with spike and slab priors is illustrated on a data set of psychiatric patients where the goal is to identify covariates affecting metabolism.
We study estimation and variable selection in non-Gaussian Bayesian generalized additive models (GAMs) under a spike-and-slab prior for grouped variables. Our framework subsumes GAMs for logistic regression, Poisson regression, negative binomial regression, and gamma regression, and encompasses both canonical and non-canonical link functions. Under mild conditions, we establish posterior contraction rates and model selection consistency when $p gg n$. For computation, we propose an EM algorithm for obtaining MAP estimates in our model, which is available in the R package sparseGAM. We illustrate our method on both synthetic and real data sets.
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