Based on the recent breakthrough of Huang (2019), we show that for any total Boolean function $f$, $bullet quad mathrm{deg}(f) = O(widetilde{mathrm{deg}}(f)^2)$: The degree of $f$ is at most quadratic in the approximate degree of $f$. This is optimal as witnessed by the OR function. $bullet quad mathrm{D}(f) = O(mathrm{Q}(f)^4)$: The deterministic query complexity of $f$ is at most quartic in the quantum query complexity of $f$. This matches the known separation (up to log factors) due to Ambainis, Balodis, Belovs, Lee, Santha, and Smotrovs (2017). We apply these results to resolve the quantum analogue of the Aanderaa--Karp--Rosenberg conjecture. We show that if $f$ is a nontrivial monotone graph property of an $n$-vertex graph specified by its adjacency matrix, then $mathrm{Q}(f)=Omega(n)$, which is also optimal. We also show that the approximate degree of any read-once formula on $n$ variables is $Theta(sqrt{n})$.