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Register a new userUnsupervised Wasserstein Distance Guided Domain Adaptation for 3D Multi-Domain Liver Segmentation
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Deep neural networks have shown exceptional learning capability and generalizability in the source domain when massive labeled data is provided. However, the well-trained models often fail in the target domain due to the domain shift. Unsupervised domain adaptation aims to improve network performance when applying robust models trained on medical images from source domains to a new target domain. In this work, we present an approach based on the Wasserstein distance guided disentangled representation to achieve 3D multi-domain liver segmentation. Concretely, we embed images onto a shared content space capturing shared feature-level information across domains and domain-specific appearance spaces. The existing mutual information-based representation learning approaches often fail to capture complete representations in multi-domain medical imaging tasks. To mitigate these issues, we utilize Wasserstein distance to learn more complete representation, and introduces a content discriminator to further facilitate the representation disentanglement. Experiments demonstrate that our method outperforms the state-of-the-art on the multi-modality liver segmentation task.
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Domain shift happens in cross-domain scenarios commonly because of the wide gaps between different domains: when applying a deep learning model well-trained in one domain to another target domain, the model usually performs poorly. To tackle this problem, unsupervised domain adaptation (UDA) techniques are proposed to bridge the gap between different domains, for the purpose of improving model performance without annotation in the target domain. Particularly, UDA has a great value for multimodal medical image analysis, where annotation difficulty is a practical concern. However, most existing UDA methods can only achieve satisfactory improvements in one adaptation direction (e.g., MRI to CT), but often perform poorly in the other (CT to MRI), limiting their practical usage. In this paper, we propose a bidirectional UDA (BiUDA) framework based on disentangled representation learning for equally competent two-way UDA performances. This framework employs a unified domain-aware pattern encoder which not only can adaptively encode images in different domains through a domain controller, but also improve model efficiency by eliminating redundant parameters. Furthermore, to avoid distortion of contents and patterns of input images during the adaptation process, a content-pattern consistency loss is introduced. Additionally, for better UDA segmentation performance, a label consistency strategy is proposed to provide extra supervision by recomposing target-domain-styled images and corresponding source-domain annotations. Comparison experiments and ablation studies conducted on two public datasets demonstrate the superiority of our BiUDA framework to current state-of-the-art UDA methods and the effectiveness of its novel designs. By successfully addressing two-way adaptations, our BiUDA framework offers a flexible solution of UDA techniques to the real-world scenario.
Unsupervised Domain Adaptation (UDA) is crucial to tackle the lack of annotations in a new domain. There are many multi-modal datasets, but most UDA approaches are uni-modal. In this work, we explore how to learn from multi-modality and propose cross-modal UDA (xMUDA) where we assume the presence of 2D images and 3D point clouds for 3D semantic segmentation. This is challenging as the two input spaces are heterogeneous and can be impacted differently by domain shift. In xMUDA, modalities learn from each other through mutual mimicking, disentangled from the segmentation objective, to prevent the stronger modality from adopting false predictions from the weaker one. We evaluate on new UDA scenarios including day-to-night, country-to-country and dataset-to-dataset, leveraging recent autonomous driving datasets. xMUDA brings large improvements over uni-modal UDA on all tested scenarios, and is complementary to state-of-the-art UDA techniques. Code is available at https://github.com/valeoai/xmuda.
Unsupervised Domain Adaptation for semantic segmentation has gained immense popularity since it can transfer knowledge from simulation to real (Sim2Real) by largely cutting out the laborious per pixel labeling efforts at real. In this work, we present a new video extension of this task, namely Unsupervised Domain Adaptation for Video Semantic Segmentation. As it became easy to obtain large-scale video labels through simulation, we believe attempting to maximize Sim2Real knowledge transferability is one of the promising directions for resolving the fundamental data-hungry issue in the video. To tackle this new problem, we present a novel two-phase adaptation scheme. In the first step, we exhaustively distill source domain knowledge using supervised loss functions. Simultaneously, video adversarial training (VAT) is employed to align the features from source to target utilizing video context. In the second step, we apply video self-training (VST), focusing only on the target data. To construct robust pseudo labels, we exploit the temporal information in the video, which has been rarely explored in the previous image-based self-training approaches. We set strong baseline scores on VIPER to CityscapeVPS adaptation scenario. We show that our proposals significantly outperform previous image-based UDA methods both on image-level (mIoU) and video-level (VPQ) evaluation metrics.
Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in real-world applications: 1) only limited labels are available for model training, due to expensive annotation costs over medical images; 2) labeled images may contain considerable label noise (e.g., mislabeling labels) due to diagnostic difficulties of diseases. To address these, we seek to exploit rich labeled data from relevant domains to help the learning in the target task via {Unsupervised Domain Adaptation} (UDA). Unlike most UDA methods that rely on clean labeled data or assume samples are equally transferable, we innovatively propose a Collaborative Unsupervised Domain Adaptation algorithm, which conducts transferability-aware adaptation and conquers label noise in a collaborative way. We theoretically analyze the generalization performance of the proposed method, and also empirically evaluate it on both medical and general images. Promising experimental results demonstrate the superiority and generalization of the proposed method.
Mask-based annotation of medical images, especially for 3D data, is a bottleneck in developing reliable machine learning models. Using minimal-labor user interactions (UIs) to guide the annotation is promising, but challenges remain on best harmonizing the mask prediction with the UIs. To address this, we propose the user-guided domain adaptation (UGDA) framework, which uses prediction-based adversarial domain adaptation (PADA) to model the combined distribution of UIs and mask predictions. The UIs are then used as anchors to guide and align the mask prediction. Importantly, UGDA can both learn from unlabelled data and also model the high-level semantic meaning behind different UIs. We test UGDA on annotating pathological livers using a clinically comprehensive dataset of 927 patient studies. Using only extreme-point UIs, we achieve a mean (worst-case) performance of 96.1%(94.9%), compared to 93.0% (87.0%) for deep extreme points (DEXTR). Furthermore, we also show UGDA can retain this state-of-the-art performance even when only seeing a fraction of available UIs, demonstrating an ability for robust and reliable UI-guided segmentation with extremely minimal labor demands.
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