We discuss proton decay in a recently proposed model of supersymmetric hybrid inflation based on the gauge symmetry $SU(4)_c times SU(2)_L times SU(2)_R$. A $U(1), R$ symmetry plays an essential role in realizing inflation as well as in eliminating some undesirable baryon number violating operators. Proton decay is primarily mediated by a variety of color triplets from chiral superfields, and it lies in the observable range for a range of intermediate scale masses for the triplets. The decay modes include $p rightarrow e^{+}(mu^+) + pi^0$, $p rightarrow bar{ u} + pi^{+}$, $p rightarrow K^0 + e^+(mu^{+})$, and $p rightarrow K^+ + bar{ u}$, with a lifetime estimate of order $10^{34}-10^{36}$ yrs and accessible at Hyper-Kamiokande and future upgrades. The unification at the Grand Unified Theory (GUT) scale $M_{rm GUT}$ ($sim 10^{16}$ GeV) of the Minimal Supersymmetric Standard Model (MSSM) gauge couplings is briefly discussed.