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Medical Imaging with Deep Learning: MIDL 2020 -- Short Paper Track

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 Added by Herve Lombaert
 Publication date 2020
and research's language is English




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This compendium gathers all the accepted extended abstracts from the Third International Conference on Medical Imaging with Deep Learning (MIDL 2020), held in Montreal, Canada, 6-9 July 2020. Note that only accepted extended abstracts are listed here, the Proceedings of the MIDL 2020 Full Paper Track are published in the Proceedings of Machine Learning Research (PMLR).



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Medical image analysis and computer-assisted intervention problems are increasingly being addressed with deep-learning-based solutions. Established deep-learning platforms are flexible but do not provide specific functionality for medical image analysis and adapting them for this application requires substantial implementation effort. Thus, there has been substantial duplication of effort and incompatible infrastructure developed across many research groups. This work presents the open-source NiftyNet platform for deep learning in medical imaging. The ambition of NiftyNet is to accelerate and simplify the development of these solutions, and to provide a common mechanism for disseminating research outputs for the community to use, adapt and build upon. NiftyNet provides a modular deep-learning pipeline for a range of medical imaging applications including segmentation, regression, image generation and representation learning applications. Components of the NiftyNet pipeline including data loading, data augmentation, network architectures, loss functions and evaluation metrics are tailored to, and take advantage of, the idiosyncracies of medical image analysis and computer-assisted intervention. NiftyNet is built on TensorFlow and supports TensorBoard visualization of 2D and 3D images and computational graphs by default. We present 3 illustrative medical image analysis applications built using NiftyNet: (1) segmentation of multiple abdominal organs from computed tomography; (2) image regression to predict computed tomography attenuation maps from brain magnetic resonance images; and (3) generation of simulated ultrasound images for specified anatomical poses. NiftyNet enables researchers to rapidly develop and distribute deep learning solutions for segmentation, regression, image generation and representation learning applications, or extend the platform to new applications.
Transfer learning from natural image datasets, particularly ImageNet, using standard large models and corresponding pretrained weights has become a de-facto method for deep learning applications to medical imaging. However, there are fundamental differences in data sizes, features and task specifications between natural image classification and the target medical tasks, and there is little understanding of the effects of transfer. In this paper, we explore properties of transfer learning for medical imaging. A performance evaluation on two large scale medical imaging tasks shows that surprisingly, transfer offers little benefit to performance, and simple, lightweight models can perform comparably to ImageNet architectures. Investigating the learned representations and features, we find that some of the differences from transfer learning are due to the over-parametrization of standard models rather than sophisticated feature reuse. We isolate where useful feature reuse occurs, and outline the implications for more efficient model exploration. We also explore feature independent benefits of transfer arising from weight scalings.
This is the second year of the TREC Deep Learning Track, with the goal of studying ad hoc ranking in the large training data regime. We again have a document retrieval task and a passage retrieval task, each with hundreds of thousands of human-labeled training queries. We evaluate using single-shot TREC-style evaluation, to give us a picture of which ranking methods work best when large data is available, with much more comprehensive relevance labeling on the small number of test queries. This year we have further evidence that rankers with BERT-style pretraining outperform other rankers in the large data regime.
We benchmark Conformer-Kernel models under the strict blind evaluation setting of the TREC 2020 Deep Learning track. In particular, we study the impact of incorporating: (i) Explicit term matching to complement matching based on learned representations (i.e., the Duet principle), (ii) query term independence (i.e., the QTI assumption) to scale the model to the full retrieval setting, and (iii) the ORCAS click data as an additional document description field. We find evidence which supports that all three aforementioned strategies can lead to improved retrieval quality.
Medical imaging is playing a more and more important role in clinics. However, there are several issues in different imaging modalities such as slow imaging speed in MRI, radiation injury in CT and PET. Therefore, accelerating MRI, reducing radiation dose in CT and PET have been ongoing research topics since their invention. Usually, acquiring less data is a direct but important strategy to address these issues. However, less acquisition usually results in aliasing artifacts in reconstructions. Recently, deep learning (DL) has been introduced in medical image reconstruction and shown potential on significantly speeding up MR reconstruction and reducing radiation dose. In this paper, we propose a general framework on combining the reconstruction model with deep learning to maximize the potential of deep learning and model-based reconstruction, and give the examples to demonstrate the performance and requirements of unrolling different algorithms using deep learning.

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