Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userPositive Contrast Susceptibility MR Imaging Using GPU-based Primal-Dual Algorithm
106
0
0.0
(
0
)
Ask ChatGPT about the research
No Arabic abstract
The susceptibility-based positive contrast MR technique was applied to estimate arbitrary magnetic susceptibility distributions of the metallic devices using a kernel deconvolution algorithm with a regularized L-1 minimization.Previously, the first-order primal-dual (PD) algorithm could provide a faster reconstruction time to solve the L-1 minimization, compared with other methods. Here, we propose to accelerate the PD algorithm of the positive contrast image using the multi-core multi-thread feature of graphics processor units (GPUs). The some experimental results showed that the GPU-based PD algorithm could achieve comparable accuracy of the metallic interventional devices in positive contrast imaging with less computational time. And the GPU-based PD approach was 4~15 times faster than the previous CPU-based scheme.
rate research
Read More
Magnetic resonance-electrical properties tomography (MR-EPT) is a technique used to estimate the conductivity and permittivity of tissues from MR measurements of the transmit magnetic field. Different reconstruction methods are available, however all these methods present several limitations which hamper the clinical applicability. Standard Helmholtz based MR-EPT methods are severely affected by noise. Iterative reconstruction methods such as contrast source inversion-EPT (CSI-EPT) are typically time consuming and are dependent on their initialization. Deep learning (DL) based methods require a large amount of training data before sufficient generalization can be achieved. Here, we investigate the benefits achievable using a hybrid approach, i.e. using MR-EPT or DL-EPT as initialization guesses for standard 3D CSI-EPT. Using realistic electromagnetic simulations at 3 T and 7 T, the accuracy and precision of hybrid CSI reconstructions are compared to standard 3D CSI-EPT reconstructions. Our results indicate that a hybrid method consisting of an initial DL-EPT reconstruction followed by a 3D CSI-EPT reconstruction would be beneficial. DL-EPT combined with standard 3D CSI-EPT exploits the power of data driven DL-based EPT reconstructions while the subsequent CSI-EPT facilitates a better generalization by providing data consistency.
Purpose: Correcting or reducing the effects of voxel intensity non-uniformity (INU) within a given tissue type is a crucial issue for quantitative MRI image analysis in daily clinical practice. In this study, we present a deep learning-based approach for MRI image INU correction. Method: We developed a residual cycle generative adversarial network (res-cycle GAN), which integrates the residual block concept into a cycle-consistent GAN (cycle-GAN). In cycle-GAN, an inverse transformation was implemented between the INU uncorrected and corrected MRI images to constrain the model through forcing the calculation of both an INU corrected MRI and a synthetic corrected MRI. A fully convolution neural network integrating residual blocks was applied in the generator of cycle-GAN to enhance end-to-end raw MRI to INU corrected MRI transformation. A cohort of 30 abdominal patients with T1-weighted MR INU images and their corrections with a clinically established and commonly used method, namely, N4ITK were used as a pair to evaluate the proposed res-cycle GAN based INU correction algorithm. Quantitatively comparisons were made among the proposed method and other approaches. Result: Our res-cycle GAN based method achieved higher accuracy and better tissue uniformity compared to the other algorithms. Moreover, once the model is well trained, our approach can automatically generate the corrected MR images in a few minutes, eliminating the need for manual setting of parameters. Conclusion: In this study, a deep learning based automatic INU correction method in MRI, namely, res-cycle GAN has been investigated. The results show that learning based methods can achieve promising accuracy, while highly speeding up the correction through avoiding the unintuitive parameter tuning process in N4ITK correction.
In this work, we propose a free-breathing magnetic resonance fingerprinting method that can be used to obtain $B_1^+$-robust quantitative maps of the abdomen in a clinically acceptable time. A three-dimensional MR fingerprinting sequence with a radial stack-of-stars trajectory was implemented for quantitative abdominal imaging. The k-space acquisition ordering was adjusted to improve motion-robustness. The flip angle pattern was optimized using the Cramer-Rao Lower Bound, and the encoding efficiency of sequences with 300, 600, 900, and 1800 flip angles was evaluated. To validate the sequence, a movable multicompartment phantom was developed. Reference multiparametric maps were acquired under stationary conditions using a previously validated MRF method. Periodic motion of the phantom was used to investigate the motion-robustness of the proposed sequence. The best performing sequence length (600 flip angles) was used to image the abdomen during a free-breathing volunteer scan. When using a series of 600 or more flip angles, the estimated $T_1$ values in the stationary phantom showed good agreement with the reference scan. Phantom experiments revealed that motion-related artefacts can appear in the quantitative maps, and confirmed that a motion-robust k-space ordering is essential in preventing these artefacts. The in vivo scan demonstrated that the proposed sequence can produce clean parameter maps while the subject breathes freely. Using this sequence, it is possible to generate $B_1^+$-robust quantitative maps of proton density, $T_1$, and $B_1^+$ under free-breathing conditions at a clinically usable resolution within 5 minutes.
The work seeks to develop an algorithm for image reconstruction by directly inverting the non-linear data model in spectral CT. Using the non-linear data model, we formulate the image-reconstruction problem as a non-convex optimization program, and develop a non-convex primal-dual (NCPD) algorithm to solve the program. We devise multiple convergence conditions and perform verification studies numerically to demonstrate that the NCPD algorithm can solve the non-convex optimization program and under appropriate data condition, can invert the non-linear data model. Using the NCPD algorithm, we then reconstruct monochromatic images from simulated and real data of numerical and physical phantoms acquired with a standard, full-scan dual-energy configuration. The result of the reconstruction studies shows that the NCPD algorithm can correct accurately for the non-linear beam-hardening effect. Furthermore, we apply the NCPD algorithm to simulated and real data of the numerical and physical phantoms collected with non-standard, short-scan dual-energy configurations, and obtain monochromatic images comparable to those of the standard, full-scan study, thus revealing the potential of the NCPD algorithm for enabling non-standard scanning configurations in spectral CT, where the existing indirect methods are limited.
The MR-Linac is a combination of an MR-scanner and radiotherapy linear accelerator (Linac) which holds the promise to increase the precision of radiotherapy treatments with MR-guided radiotherapy by monitoring motion during radiotherapy with MRI, and adjusting the radiotherapy plan accordingly. Optimal MR-guidance for respiratory motion during radiotherapy requires MR-based 3D motion estimation with a latency of 200-500 ms. Currently this is still challenging since typical methods rely on MR-images, and are therefore limited by the 3D MR-imaging latency. In this work, we present a method to perform non-rigid 3D respiratory motion estimation with 170 ms latency, including both acquisition and reconstruction. The proposed method called real-time low-rank MR-MOTUS reconstructs motion-fields directly from k-space data, and leverages an explicit low-rank decomposition of motion-fields to split the large scale 3D+t motion-field reconstruction problem posed in our previous work into two parts: (I) a medium-scale offline preparation phase and (II) a small-scale online inference phase which exploits the results of the offline phase for real-time computations. The method was validated on free-breathing data of five volunteers, acquired with a 1.5T Elekta Unity MR-Linac. Results show that the reconstructed 3D motion-field are anatomically plausible, highly correlated with a self-navigation motion surrogate (R = 0.975 +/- 0.0110), and can be reconstructed with a total latency of 170 ms that is sufficient for real-time MR-guided abdominal radiotherapy.
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
