A first search for $CP$ violation in the Cabibbo-suppressed $Xi_c^+rightarrow pK^-pi^+$ decay is performed using both a binned and an unbinned model-independent technique in the Dalitz plot. The studies are based on a sample of proton-proton collision data, corresponding to an integrated luminosity of $3.0~{rm fb^{-1}}$, and collected by the LHCb experiment at centre-of-mass energies of $7$ and $8~rm TeV$. The data are consistent with the hypothesis of no $CP$ violation.