Poisoning attacks have emerged as a significant security threat to machine learning (ML) algorithms. It has been demonstrated that adversaries who make small changes to the training set, such as adding specially crafted data points, can hurt the performance of the output model. Most of these attacks require the full knowledge of training data or the underlying data distribution. In this paper we study the power of oblivious adversaries who do not have any information about the training set. We show a separation between oblivious and full-information poisoning adversaries. Specifically, we construct a sparse linear regression problem for which LASSO estimator is robust against oblivious adversaries whose goal is to add a non-relevant features to the model with certain poisoning budget. On the other hand, non-oblivious adversaries, with the same budget, can craft poisoning examples based on the rest of the training data and successfully add non-relevant features to the model.