Recently, superconductivity was discovered at very low densities in slightly misaligned graphene multilayers. Surprisingly, despite extremely low electronic density (about $10^{-4}$ electrons per unit cell), these systems realize strong-coupling superconductivity, with the transition temperature being a large fraction of the Fermi energy ($T_csim 0.1 epsilon_F$). Here we propose a qualitative explanation for this remarkable phenomenon, highlighting similarities and qualitative differences with the conventional uniform high-density superconductivity. Most importantly, we find that periodic superimposed potential generically enhances local interactions relative to nonlocal (for instance, Coulomb) interactions. In addition, the density of states is enhanced as well, exponentially in modulation strength for low lying bands in some cases. Combination of these two effects makes moire systems natural intermediate or strong-coupled superconductors, with potential for very high transition temperatures.