No Arabic abstract
Knowledge Graph Completion (KGC) has been proposed to improve Knowledge Graphs by filling in missing connections via link prediction or relation extraction. One of the main difficulties for KGC is a low resource problem. Previous approaches assume sufficient training triples to learn versatile vectors for entities and relations, or a satisfactory number of labeled sentences to train a competent relation extraction model. However, low resource relations are very common in KGs, and those newly added relations often do not have many known samples for training. In this work, we aim at predicting new facts under a challenging setting where only limited training instances are available. We propose a general framework called Weighted Relation Adversarial Network, which utilizes an adversarial procedure to help adapt knowledge/features learned from high resource relations to different but related low resource relations. Specifically, the framework takes advantage of a relation discriminator to distinguish between samples from different relations, and help learn relation-invariant features more transferable from source relations to target relations. Experimental results show that the proposed approach outperforms previous methods regarding low resource settings for both link prediction and relation extraction.
Many graph embedding approaches have been proposed for knowledge graph completion via link prediction. Among those, translating embedding approaches enjoy the advantages of light-weight structure, high efficiency and great interpretability. Especially when extended to complex vector space, they show the capability in handling various relation patterns including symmetry, antisymmetry, inversion and composition. However, previous translating embedding approaches defined in complex vector space suffer from two main issues: 1) representing and modeling capacities of the model are limited by the translation function with rigorous multiplication of two complex numbers; and 2) embedding ambiguity caused by one-to-many relations is not explicitly alleviated. In this paper, we propose a relation-adaptive translation function built upon a novel weighted product in complex space, where the weights are learnable, relation-specific and independent to embedding size. The translation function only requires eight more scalar parameters each relation, but improves expressive power and alleviates embedding ambiguity problem. Based on the function, we then present our Relation-adaptive translating Embedding (RatE) approach to score each graph triple. Moreover, a novel negative sampling method is proposed to utilize both prior knowledge and self-adversarial learning for effective optimization. Experiments verify RatE achieves state-of-the-art performance on four link prediction benchmarks.
Few-shot Knowledge Graph (KG) completion is a focus of current research, where each task aims at querying unseen facts of a relation given its few-shot reference entity pairs. Recent attempts solve this problem by learning static representations of entities and references, ignoring their dynamic properties, i.e., entities may exhibit diverse roles within task relations, and references may make different contributions to queries. This work proposes an adaptive attentional network for few-shot KG completion by learning adaptive entity and reference representations. Specifically, entities are modeled by an adaptive neighbor encoder to discern their task-oriented roles, while references are modeled by an adaptive query-aware aggregator to differentiate their contributions. Through the attention mechanism, both entities and references can capture their fine-grained semantic meanings, and thus render more expressive representations. This will be more predictive for knowledge acquisition in the few-shot scenario. Evaluation in link prediction on two public datasets shows that our approach achieves new state-of-the-art results with different few-shot sizes.
Knowledge graphs are important resources for many artificial intelligence tasks but often suffer from incompleteness. In this work, we propose to use pre-trained language models for knowledge graph completion. We treat triples in knowledge graphs as textual sequences and propose a novel framework named Knowledge Graph Bidirectional Encoder Representations from Transformer (KG-BERT) to model these triples. Our method takes entity and relation descriptions of a triple as input and computes scoring function of the triple with the KG-BERT language model. Experimental results on multiple benchmark knowledge graphs show that our method can achieve state-of-the-art performance in triple classification, link prediction and relation prediction tasks.
Predicting missing facts in a knowledge graph (KG) is a crucial task in knowledge base construction and reasoning, and it has been the subject of much research in recent works using KG embeddings. While existing KG embedding approaches mainly learn and predict facts within a single KG, a more plausible solution would benefit from the knowledge in multiple language-specific KGs, considering that different KGs have their own strengths and limitations on data quality and coverage. This is quite challenging, since the transfer of knowledge among multiple independently maintained KGs is often hindered by the insufficiency of alignment information and the inconsistency of described facts. In this paper, we propose KEnS, a novel framework for embedding learning and ensemble knowledge transfer across a number of language-specific KGs. KEnS embeds all KGs in a shared embedding space, where the association of entities is captured based on self-learning. Then, KEnS performs ensemble inference to combine prediction results from embeddings of multiple language-specific KGs, for which multiple ensemble techniques are investigated. Experiments on five real-world language-specific KGs show that KEnS consistently improves state-of-the-art methods on KG completion, via effectively identifying and leveraging complementary knowledge.
Objective: To discover candidate drugs to repurpose for COVID-19 using literature-derived knowledge and knowledge graph completion methods. Methods: We propose a novel, integrative, and neural network-based literature-based discovery (LBD) approach to identify drug candidates from both PubMed and COVID-19-focused research literature. Our approach relies on semantic triples extracted using SemRep (via SemMedDB). We identified an informative subset of semantic triples using filtering rules and an accuracy classifier developed on a BERT variant, and used this subset to construct a knowledge graph. Five SOTA, neural knowledge graph completion algorithms were used to predict drug repurposing candidates. The models were trained and assessed using a time slicing approach and the predicted drugs were compared with a list of drugs reported in the literature and evaluated in clinical trials. These models were complemented by a discovery pattern-based approach. Results: Accuracy classifier based on PubMedBERT achieved the best performance (F1= 0.854) in classifying semantic predications. Among five knowledge graph completion models, TransE outperformed others (MR = 0.923, Hits@1=0.417). Some known drugs linked to COVID-19 in the literature were identified, as well as some candidate drugs that have not yet been studied. Discovery patterns enabled generation of plausible hypotheses regarding the relationships between the candidate drugs and COVID-19. Among them, five highly ranked and novel drugs (paclitaxel, SB 203580, alpha 2-antiplasmin, pyrrolidine dithiocarbamate, and butylated hydroxytoluene) with their mechanistic explanations were further discussed. Conclusion: We show that an LBD approach can be feasible for discovering drug candidates for COVID-19, and for generating mechanistic explanations. Our approach can be generalized to other diseases as well as to other clinical questions.