We study neutrino oscillations in a medium of dark matter which generalizes the standard matter effect. A general formula is derived to describe the effect of various mediums and their mediators to neutrinos. Neutrinos and anti-neutrinos receive opposite contributions from asymmetric distribution of (dark) matter and anti-matter, and thus it could appear in precision measurement of neutrino or anti-neutrino oscillations. Furthermore, the standard neutrino oscillation can occur from the symmetric dark matter effect even for massless neutrinos.
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