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Register a new userDevelopment and characterization of six-gap glass MRPCs and feasibility study of a PET device
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The Multigap Resistive Plate Chambers (MRPCs) provide excellent timing as well as position resolutions at relatively low cost. Therefore, they can be used in medical imaging applications such as PET where precise timing is a crucial parameter of measurement. We have designed and fabricated several six-gap glass MRPCs and extensively studied their performance. In this paper, we describe the fabrication and characterization of the detector, the electronics and the data acquisition system of the setup. We present here the result of our Time Of Flight (TOF) experiment using a radioactive source Na-22 hence to demonstrate their potential applications in medical imaging. We also present the Geant4 based simulation results on the efficiency of our detector as a function of the number of gaps and thickness of the converter material.
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The Multi-gap Resistive Plate Chamber (MRPC) is an advanced form of Resistive Plate Chamber (RPC) detector where the gas gap is divided into sub-gaps. MRPCs are known for their good time resolution and detection efficiency for charged particles. They have found suitable applications in several high energy physics experiments like ALICE in LHC, CERN, Geneva, Switzerland, and STAR in RHIC, BNL, USA. As they have very good time resolution and are of low cost, they can be a suitable replacement for very expensive scintillators used in Positron Emission Tomography Imaging. The MRPCs that are being used nowadays are developed with glass electrodes. We have made an attempt to develop a 6-gap MRPC using bakelite electrodes. The outer electrodes are of dimensions 15 cm $times$ 15 cm $times$ 0.3 cm and the inner electrodes are of dimension 14 cm $times$ 14 cm $times$ 0.05 cm. The glossy finished electrode surfaces have not been treated with any oil like linseed, silicone for smoothness. The performance of the detector has been studied measuring the efficiency, noise rate and time resolution with cosmic rays. This effort is towards the development of a prototype for Positron Emission Tomography with the Time-Of-Flight technique using MRPCs. Details of the development procedure and performance studies have been presented here.
This article reports on the feasibility of testing of the symmetry under reversal in time in a purely leptonic system constituted by positronium atoms using the J-PET detector. The present state of T symmetry tests is discussed with an emphasis on the scarcely explored sector of leptonic systems. Two possible strategies of searching for manifestations of T violation in non-vanishing angular correlations of final state observables in the decays of metastable triplet states of positronium available with J-PET are proposed and discussed. Results of a pilot measurement with J-PET and assessment of its performance in reconstruction of three-photon decays are shown along with an analysis of its impact on the sensitivity of the detector for the determination of T -violation sensitive observables.
A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the object. In this paper we explore the possibility of performing the three gamma photons imaging based on ortho-positronium annihilation, as well as the possibility of positronium mean lifetime imaging with the J-PET tomograph constructed from plastic scintillators. For this purposes simulations of the ortho-positronium formation and its annihilation into three photons were performed taking into account distributions of photons momenta as predicted by the theory of quantum electrodynamics and the response of the J-PET tomograph. In order to test the proposed ortho-positronium lifetime image reconstruction method, we concentrate on the decay of the ortho-positronium into three photons and applications of radiopharmaceuticals labeled with isotopes emitting a prompt gamma quantum. The proposed method of imaging is based on the determination of hit-times and hit-positions of registered photons which enables the reconstruction of the time and position of the annihilation point as well as the lifetime of the ortho-positronium on an event-by-event basis. We have simulated the production of the positronium in a cylindrical phantom composed of a set of different materials in which the ortho-positronium lifetime varied from 2.0 ns to 3.0 ns, as expected for ortho-positronium created in the human body. The presented reconstruction method for total-body J-PET like detector allows to achieve a mean lifetime resolution of about 40 ps. Recent Positron Annihilation Lifetime Spectroscopy measurements of cancerous and healthy uterine tissues show that this sensitivity may allow to study the morphological changes in cell structures.
The Jagiellonian Positron Emission Tomograph (J-PET) is a novel de- vice being developed at Jagiellonian University in Krakow, Poland based on or- ganic scintillators. J-PET is an axially symmetric and high acceptance scanner that can be used as a multi-purpose detector system. It is well suited to pur- sue tests of discrete symmetries in decays of positronium in addition to medical imaging. J-PET enables the measurement of both momenta and the polarization vectors of annihilation photons. The latter is a unique feature of the J-PET detector which allows the study of time reversal symmetry violation operator which can be constructed solely from the annihilation photons momenta before and after the scattering in the detector.
We explore the feasibility of a next-generation Mu2e experiment that uses Project-X beams to achieve a sensitivity approximately a factor ten better than the currently planned Mu2e facility.
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