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Register a new userSignet Ring Cell Detection With a Semi-supervised Learning Framework
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Added by
Jiahui Li
Publication date
2019
fields
Informatics Engineering
and research's language is
English
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Signet ring cell carcinoma is a type of rare adenocarcinoma with poor prognosis. Early detection leads to huge improvement of patients survival rate. However, pathologists can only visually detect signet ring cells under the microscope. This procedure is not only laborious but also prone to omission. An automatic and accurate signet ring cell detection solution is thus important but has not been investigated before. In this paper, we take the first step to present a semi-supervised learning framework for the signet ring cell detection problem. Self-training is proposed to deal with the challenge of incomplete annotations, and cooperative-training is adapted to explore the unlabeled regions. Combining the two techniques, our semi-supervised learning framework can make better use of both labeled and unlabeled data. Experiments on large real clinical data demonstrate the effectiveness of our design. Our framework achieves accurate signet ring cell detection and can be readily applied in the clinical trails. The dataset will be released soon to facilitate the development of the area.
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Semi-supervised learning (SSL) has a potential to improve the predictive performance of machine learning models using unlabeled data. Although there has been remarkable recent progress, the scope of demonstration in SSL has mainly been on image classification tasks. In this paper, we propose STAC, a simple yet effective SSL framework for visual object detection along with a data augmentation strategy. STAC deploys highly confident pseudo labels of localized objects from an unlabeled image and updates the model by enforcing consistency via strong augmentations. We propose experimental protocols to evaluate the performance of semi-supervised object detection using MS-COCO and show the efficacy of STAC on both MS-COCO and VOC07. On VOC07, STAC improves the AP$^{0.5}$ from $76.30$ to $79.08$; on MS-COCO, STAC demonstrates $2{times}$ higher data efficiency by achieving 24.38 mAP using only 5% labeled data than supervised baseline that marks 23.86% using 10% labeled data. The code is available at https://github.com/google-research/ssl_detection/.
With availability of huge amounts of labeled data, deep learning has achieved unprecedented success in various object detection tasks. However, large-scale annotations for medical images are extremely challenging to be acquired due to the high demand of labour and expertise. To address this difficult issue, in this paper we propose a novel semi-supervised deep metric learning method to effectively leverage both labeled and unlabeled data with application to cervical cancer cell detection. Different from previous methods, our model learns an embedding metric space and conducts dual alignment of semantic features on both the proposal and prototype levels. First, on the proposal level, we generate pseudo labels for the unlabeled data to align the proposal features with learnable class proxies derived from the labeled data. Furthermore, we align the prototypes generated from each mini-batch of labeled and unlabeled data to alleviate the influence of possibly noisy pseudo labels. Moreover, we adopt a memory bank to store the labeled prototypes and hence significantly enrich the metric learning information from larger batches. To comprehensively validate the method, we construct a large-scale dataset for semi-supervised cervical cancer cell detection for the first time, consisting of 240,860 cervical cell images in total. Extensive experiments show our proposed method outperforms other state-of-the-art semi-supervised approaches consistently, demonstrating efficacy of deep semi-supervised metric learning with dual alignment on improving cervical cancer cell detection performance.
The use of supervised learning with various sensing techniques such as audio, visual imaging, thermal sensing, RADAR, and radio frequency (RF) have been widely applied in the detection of unmanned aerial vehicles (UAV) in an environment. However, little or no attention has been given to the application of unsupervised or semi-supervised algorithms for UAV detection. In this paper, we proposed a semi-supervised technique and architecture for detecting UAVs in an environment by exploiting the RF signals (i.e., fingerprints) between a UAV and its flight-controller communication under wireless inference such as Bluetooth and WiFi. By decomposing the RF signals using a two-level wavelet packet transform, we estimated the second moment statistic (i.e., variance) of the coefficients in each packet as a feature set. We developed a local outlier factor model as the UAV detection algorithm using the coefficient variances of the wavelet packets from WiFi and Bluetooth signals. When detecting the presence of RF-based UAV, we achieved an accuracy of 96.7$%$ and 86$%$ at a signal-to-noise ratio of 30~dB and 18~dB, respectively. The application of this approach is not limited to UAV detection as it can be extended to the detection of rogue RF devices in an environment.
Cell event detection in cell videos is essential for monitoring of cellular behavior over extended time periods. Deep learning methods have shown great success in the detection of cell events for their ability to capture more discriminative features of cellular processes compared to traditional methods. In particular, convolutional long short-term memory (LSTM) models, which exploits the changes in cell events observable in video sequences, is the state-of-the-art for mitosis detection in cell videos. However, their limitations are the determination of the input sequence length, which is often performed empirically, and the need for a large annotated training dataset which is expensive to prepare. We propose a novel semi-supervised method of optimal length detection for mitosis detection with two key contributions: (i) an unsupervised step for learning the spatial and temporal locations of cells in their normal stage and approximating the distribution of temporal lengths of cell events and, (ii) a step of inferring, from that distribution, an optimal input sequence length and a minimal number of annotated frames for training a LSTM model for each particular video. We evaluated our method in detecting mitosis in densely packed stem cells in a phase-contrast microscopy videos. Our experimental data prove that increasing the input sequence length of LSTM can lead to a decrease in performance. Our results also show that by approximating the optimal input sequence length of the tested video, a model trained with only 18 annotated frames achieved F1-scores of 0.880-0.907, which are 10% higher than those of other published methods with a full set of 110 training annotated frames.
Despite the data labeling cost for the object detection tasks being substantially more than that of the classification tasks, semi-supervised learning methods for object detection have not been studied much. In this paper, we propose an Interpolation-based Semi-supervised learning method for object Detection (ISD), which considers and solves the problems caused by applying conventional Interpolation Regularization (IR) directly to object detection. We divide the output of the model into two types according to the objectness scores of both original patches that are mixed in IR. Then, we apply a separate loss suitable for each type in an unsupervised manner. The proposed losses dramatically improve the performance of semi-supervised learning as well as supervised learning. In the supervised learning setting, our method improves the baseline methods by a significant margin. In the semi-supervised learning setting, our algorithm improves the performance on a benchmark dataset (PASCAL VOC and MSCOCO) in a benchmark architecture (SSD).
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