The Belle II experiment at the SuperKEKB energy-asymmetric $e^+e^-$ collider is a substantial upgrade of the B factory facility at the Japanese KEK laboratory. The design luminosity of the machine is $8times10^{35}, mathrm{cm}^{-2}mathrm{s}^{-1}$ and the Belle II experiment aims to record $50, mathrm{ab}^{-1}$ of data, a factor of 50 more than its predecessor. From February to July 2018, SuperKEKB has completed a commissioning run, achieved a peak luminosity of $5.5 times 10^{33}, mathrm{cm}^{-2}mathrm{s}^{-1}$, and Belle II recorded a data sample of about $0.5, mathrm{fb}^{-1}$. In this presentation we show first results from studying missing energy signatures, such as leptonic and semileptonic B meson decays based on this early Belle II data. We report first studies on re-measuring important standard candle processes, such as the abundant inclusive $Brightarrow X l u$ and $Bto D^*ell u$ decays, and evaluate the performance of machine learning-based tagging algorithms. Furthermore, we also present an overview of the semileptonic B decays that will be measured in the upcoming years at Belle II and discuss prospects for important B-anomalies like R$(D)$ and R$(D^*)$, as well as other tests of lepton flavor universality.
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