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Magnetic Resonance Fingerprinting using Recurrent Neural Networks

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 Added by Ilkay Oksuz
 Publication date 2018
and research's language is English




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Magnetic Resonance Fingerprinting (MRF) is a new approach to quantitative magnetic resonance imaging that allows simultaneous measurement of multiple tissue properties in a single, time-efficient acquisition. Standard MRF reconstructs parametric maps using dictionary matching and lacks scalability due to computational inefficiency. We propose to perform MRF map reconstruction using a recurrent neural network, which exploits the time-dependent information of the MRF signal evolution. We evaluate our method on multiparametric synthetic signals and compare it to existing MRF map reconstruction approaches, including those based on neural networks. Our method achieves state-of-the-art estimates of T1 and T2 values. In addition, the reconstruction time is significantly reduced compared to dictionary-matching based approaches.



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149 - Elisabeth Hoppe 2019
Recently, Magnetic Resonance Fingerprinting (MRF) was proposed as a quantitative imaging technique for the simultaneous acquisition of tissue parameters such as relaxation times $T_1$ and $T_2$. Although the acquisition is highly accelerated, the state-of-the-art reconstruction suffers from long computation times: Template matching methods are used to find the most similar signal to the measured one by comparing it to pre-simulated signals of possible parameter combinations in a discretized dictionary. Deep learning approaches can overcome this limitation, by providing the direct mapping from the measured signal to the underlying parameters by one forward pass through a network. In this work, we propose a Recurrent Neural Network (RNN) architecture in combination with a novel quantile layer. RNNs are well suited for the processing of time-dependent signals and the quantile layer helps to overcome the noisy outliers by considering the spatial neighbors of the signal. We evaluate our approach using in-vivo data from multiple brain slices and several volunteers, running various experiments. We show that the RNN approach with small patches of complex-valued input signals in combination with a quantile layer outperforms other architectures, e.g. previously proposed CNNs for the MRF reconstruction reducing the error in $T_1$ and $T_2$ by more than 80%.
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