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Register a new userA High Accuracy and High Sensitivity System Architecture for Electrical Impedance Tomography System
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A high accuracy and high sensitivity system architecture is proposed for the read-out circuit of electrical impedance tomography system-on-chip. The switched ratiometric technique is applied in the proposed architecture. The proposed system architecture minimizes the device noise by processing signals from both read-out electrodes and the stimulus. The quantized signals are post-processed in the digital processing unit for proper signal demodulation and impedance ratio calculation. Our proposed architecture improves the sensitivity of the read-out circuit, cancels out the gain fluctuations in the system, and overcomes the effects of motion artifacts on measurements.
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The accuracy of estimating $d$-dimensional quantum states is limited by the Gill-Massar bound. It can be saturated in the qubit ($d=2$) scenario using adaptive standard quantum tomography. In higher dimensions, however, this is not the case and the accuracy achievable with adaptive quantum tomography quickly deteriorates with increasing $d$. Moreover, it is not known whether or not the Gill-Massar bound can be reached for an arbitrary $d$. To overcome this limitation, we introduce an adaptive tomographic method that is characterized by a precision that is better than half that of the Gill-Massar bound for any finite dimension. This provides a new achievable accuracy limit for quantum state estimation. We demonstrate the high-accuracy of our method by estimating the state of 10-dimensional quantum systems. With the advent of new technologies capable of high-dimensional quantum information processing, our results become critically relevant as state reconstruction is an essential tool for certifying the proper operation of quantum devices.
Computer tomography is one of the most promising new methods to image abnormal tissues inside the human body. Tomography is also used to position the patient accurately before radiation therapy. Hadron therapy for treating cancer has become one of the most advantageous and safe options. In order to fully utilize the advantages of hadron therapy, there is a necessity of performing radiography with hadrons as well. In this paper we present the development of a proton computed tomography system. Our second-generation proton tomography system consists of two upstream and two downstream trackers made up of fibers as active material and a range detector consisting of plastic scintillators. We present details of the detector system, readout electronics, and data acquisition system as well as the commissioning of the entire system. We also present preliminary results from the test beam of the range detector.
A novel computational, non-iterative and noise-robust reconstruction method is introduced for the planar anisotropic inverse conductivity problem. The method is based on bypassing the unstable step of the reconstruction of the values of the isothermal coordinates on the boundary of the domain. Non-uniqueness of the inverse problem is dealt with by recovering the unique isotropic conductivity that can be achieved as a deformation of the measured anisotropic conductivity by emph{isothermal coordinates}. The method shows how isotropic D-bar reconstruction methods have produced reasonable and informative reconstructions even when used on EIT data known to come from anisotropic media, and when the boundary shape is not known precisely. Furthermore, the results pave the way for regularized anisotropic EIT. Key aspects of the approach involve D-bar methods and inverse scattering theory, complex geometrical optics solutions, and quasi-conformal mapping techniques.
Although cone-beam CT (CBCT) has been used to guide irradiation for pre-clinical radiotherapy(RT) research, it is limited to localize soft tissue target especially in a low imaging contrast environment. Knowledge of target shape is a fundamental need for RT. Without such information to guide radiation, normal tissue can be irradiated unnecessarily, leading to experimental uncertainties. Recognition of this need led us to develop quantitative bioluminescence tomography (QBLT), which provides strong imaging contrast to localize optical targets. We demonstrated its capability of guiding conformal RT using an orthotopic bioluminescent glioblastoma (GBM) model. With multi-projection and multi-spectral bioluminescence imaging and a novel spectral derivative method, our QBLT system is able to reconstruct GBM with localization accuracy <1mm. An optimal threshold was determined to delineate QBLT reconstructed gross target volume (GTV_{QBLT}), which provides the best overlap between the GTV_{QBLT} and CBCT contrast labeled GBM (GTV), used as the ground truth for the GBM volume. To account for the uncertainty of QBLT in target localization and volume delineation, we also innovated a margin design; a 0.5mm margin was determined and added to GTV_{QBLT} to form a planning target volume (PTV_{QBLT}), which largely improved tumor coverage from 75% (0mm margin) to 98% and the corresponding variation (n=10) of the tumor coverage was significantly reduced. Moreover, with prescribed dose 5Gy covering 95% of PTV_{QBLT}, QBLT-guided 7-field conformal RT can irradiate 99.4 pm 1.0% of GTV vs. 65.5 pm 18.5% with conventional single field irradiation (n=10). Our QBLT-guided system provides a unique opportunity for researchers to guide irradiation for soft tissue targets and increase rigorous and reproducibility of scientific discovery.
High Altitude Platform Station (HAPS) has the potential to provide global wireless connectivity and data services such as high-speed wireless backhaul, industrial Internet of things (IoT), and public safety for large areas not served by terrestrial networks. A unified HAPS design is desired to support various use cases and a wide range of requirements. In this paper, we present two architecture designs of the HAPS system: i) repeater based HAPS, and ii) base station based HAPS, which are both viable technical solutions. The energy efficiency is analyzed and compared between the two architectures using consumption factor theory. The system performance of these two architectures is evaluated through Monte Carlo simulations and is characterized in metrics of spectral efficiency using LTE band 1 for both single-cell and multi-cell cases. Both designs can provide good downlink spectral efficiency and coverage, while the uplink coverage is significantly limited by UE transmit power and antenna gain. Using directional antennas at the UEs can improve the system performance for both downlink and uplink.
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