We use the holographic V-QCD models to analyse the physics of dense QCD and neutron stars. Accommodating lattice results for thermodynamics of QCD enables us to make generic predictions for the Equation of State (EoS) of the quark matter phase in the cold and dense regime. We demonstrate that the resulting pressure in V-QCD matches well with a family of neutron-star-matter EoSs that interpolate between state-of-the-art theoretical results for low and high density QCD. After implementing the astrophysical constraints, i.e., the largest known neutron star mass and the recent LIGO/Virgo results for the tidal deformability, we analyse the phase transition between the baryonic and quark matter phases. We find that the baryon density $n_B$ at the transition is at least 2.9 times the nuclear saturation density $n_s$. The transition is of strongly first order at low and intermediate densities, i.e., for $n_B/n_s lesssim 7.5$.
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