Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userCT Image Enhancement Using Stacked Generative Adversarial Networks and Transfer Learning for Lesion Segmentation Improvement
129
0
0.0
(
0
)
Added by
Youbao Tang
Publication date
2018
fields
Informatics Engineering
and research's language is
English
Ask ChatGPT about the research
No Arabic abstract
Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can exhibit high noise and low contrast, particularly in lower dosages. To address this, we focus on a preprocessing method for CT images that uses stacked generative adversarial networks (SGAN) approach. The first GAN reduces the noise in the CT image and the second GAN generates a higher resolution image with enhanced boundaries and high contrast. To make up for the absence of high quality CT images, we detail how to synthesize a large number of low- and high-quality natural images and use transfer learning with progressively larger amounts of CT images. We apply both the classic GrabCut method and the modern holistically nested network (HNN) to lesion segmentation, testing whether SGAN can yield improved lesion segmentation. Experimental results on the DeepLesion dataset demonstrate that the SGAN enhancements alone can push GrabCut performance over HNN trained on original images. We also demonstrate that HNN + SGAN performs best compared against four other enhancement methods, including when using only a single GAN.
rate research
Read More
Lesion segmentation on computed tomography (CT) scans is an important step for precisely monitoring changes in lesion/tumor growth. This task, however, is very challenging since manual segmentation is prohibitively time-consuming, expensive, and requires professional knowledge. Current practices rely on an imprecise substitute called response evaluation criteria in solid tumors (RECIST). Although these markers lack detailed information about the lesion regions, they are commonly found in hospitals picture archiving and communication systems (PACS). Thus, these markers have the potential to serve as a powerful source of weak-supervision for 2D lesion segmentation. To approach this problem, this paper proposes a convolutional neural network (CNN) based weakly-supervised lesion segmentation method, which first generates the initial lesion masks from the RECIST measurements and then utilizes co-segmentation to leverage lesion similarities and refine the initial masks. In this work, an attention-based co-segmentation model is adopted due to its ability to learn more discriminative features from a pair of images. Experimental results on the NIH DeepLesion dataset demonstrate that the proposed co-segmentation approach significantly improves lesion segmentation performance, e.g the Dice score increases about 4.0% (from 85.8% to 89.8%).
Data availability plays a critical role for the performance of deep learning systems. This challenge is especially acute within the medical image domain, particularly when pathologies are involved, due to two factors: 1) limited number of cases, and 2) large variations in location, scale, and appearance. In this work, we investigate whether augmenting a dataset with artificially generated lung nodules can improve the robustness of the progressive holistically nested network (P-HNN) model for pathological lung segmentation of CT scans. To achieve this goal, we develop a 3D generative adversarial network (GAN) that effectively learns lung nodule property distributions in 3D space. In order to embed the nodules within their background context, we condition the GAN based on a volume of interest whose central part containing the nodule has been erased. To further improve realism and blending with the background, we propose a novel multi-mask reconstruction loss. We train our method on over 1000 nodules from the LIDC dataset. Qualitative results demonstrate the effectiveness of our method compared to the state-of-art. We then use our GAN to generate simulated training images where nodules lie on the lung border, which are cases where the published P-HNN model struggles. Qualitative and quantitative results demonstrate that armed with these simulated images, the P-HNN model learns to better segment lung regions under these challenging situations. As a result, our system provides a promising means to help overcome the data paucity that commonly afflicts medical imaging.
Image extension models have broad applications in image editing, computational photography and computer graphics. While image inpainting has been extensively studied in the literature, it is challenging to directly apply the state-of-the-art inpainting methods to image extension as they tend to generate blurry or repetitive pixels with inconsistent semantics. We introduce semantic conditioning to the discriminator of a generative adversarial network (GAN), and achieve strong results on image extension with coherent semantics and visually pleasing colors and textures. We also show promising results in extreme extensions, such as panorama generation.
We present a learned image compression system based on GANs, operating at extremely low bitrates. Our proposed framework combines an encoder, decoder/generator and a multi-scale discriminator, which we train jointly for a generative learned compression objective. The model synthesizes details it cannot afford to store, obtaining visually pleasing results at bitrates where previous methods fail and show strong artifacts. Furthermore, if a semantic label map of the original image is available, our method can fully synthesize unimportant regions in the decoded image such as streets and trees from the label map, proportionally reducing the storage cost. A user study confirms that for low bitrates, our approach is preferred to state-of-the-art methods, even when they use more than double the bits.
Great progress has been made by the advances in Generative Adversarial Networks (GANs) for image generation. However, there lacks enough understanding on how a realistic image can be generated by the deep representations of GANs from a random vector. This chapter will give a summary of recent works on interpreting deep generative models. We will see how the human-understandable concepts that emerge in the learned representation can be identified and used for interactive image generation and editing.
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
