This paper is concerned with the initial value problem for semilinear wave equation with structural damping $u_{tt}+(-Delta)^{sigma}u_t -Delta u =f(u)$, where $sigma in (0,frac{1}{2})$ and $f(u) sim |u|^p$ or $u |u|^{p-1}$ with $p> 1 + {2}/(n - 2 sigma)$. We first show the global existence for initial data small in some weighted Sobolev spaces on $mathcal R^n$ ($n ge 2$). Next, we show that the asymptotic profile of the solution above is given by a constant multiple of the fundamental solution of the corresponding parabolic equation, provided the initial data belong to weighted $L^1$ spaces.