We study the Ext modules in the category of left modules over a twisted algebra of a finite quiver over a ringed space $(X,mathcal O_X)$, allowing for the presence of relations. We introduce a spectral sequence which relates the Ext modules in that category with the Ext modules in the category of $mathcal O_X$-modules. Contrary to what happens in the absence of relations, this spectral sequence in general does not degenerate at the second page. We also consider local Ext sheaves. Under suitable hypotheses, the Ext modules are represented as hypercohomology groups