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Register a new userA Sentiment Analysis of Breast Cancer Treatment Experiences and Healthcare Perceptions Across Twitter
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Eric Clark Mr.
Publication date
2018
fields
Informatics Engineering
and research's language is
English
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Background: Social media has the capacity to afford the healthcare industry with valuable feedback from patients who reveal and express their medical decision-making process, as well as self-reported quality of life indicators both during and post treatment. In prior work, [Crannell et. al.], we have studied an active cancer patient population on Twitter and compiled a set of tweets describing their experience with this disease. We refer to these online public testimonies as Invisible Patient Reported Outcomes (iPROs), because they carry relevant indicators, yet are difficult to capture by conventional means of self-report. Methods: Our present study aims to identify tweets related to the patient experience as an additional informative tool for monitoring public health. Using Twitters public streaming API, we compiled over 5.3 million breast cancer related tweets spanning September 2016 until mid December 2017. We combined supervised machine learning methods with natural language processing to sift tweets relevant to breast cancer patient experiences. We analyzed a sample of 845 breast cancer patient and survivor accounts, responsible for over 48,000 posts. We investigated tweet content with a hedonometric sentiment analysis to quantitatively extract emotionally charged topics. Results: We found that positive experiences were shared regarding patient treatment, raising support, and spreading awareness. Further discussions related to healthcare were prevalent and largely negative focusing on fear of political legislation that could result in loss of coverage. Conclusions: Social media can provide a positive outlet for patients to discuss their needs and concerns regarding their healthcare coverage and treatment needs. Capturing iPROs from online communication can help inform healthcare professionals and lead to more connected and personalized treatment regimens.
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Sentiment analysis is a text mining task that determines the polarity of a given text, i.e., its positiveness or negativeness. Recently, it has received a lot of attention given the interest in opinion mining in micro-blogging platforms. These new forms of textual expressions present new challenges to analyze text given the use of slang, orthographic and grammatical errors, among others. Along with these challenges, a practical sentiment classifier should be able to handle efficiently large workloads. The aim of this research is to identify which text transformations (lemmatization, stemming, entity removal, among others), tokenizers (e.g., words $n$-grams), and tokens weighting schemes impact the most the accuracy of a classifier (Support Vector Machine) trained on two Spanish corpus. The methodology used is to exhaustively analyze all the combinations of the text transformations and their respective parameters to find out which characteristics the best performing classifiers have in common. Furthermore, among the different text transformations studied, we introduce a novel approach based on the combination of word based $n$-grams and character based $q$-grams. The results show that this novel combination of words and characters produces a classifier that outperforms the traditional word based combination by $11.17%$ and $5.62%$ on the INEGI and TASS15 dataset, respectively.
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Early detection of breast cancer through screening mammography yields a 20-35% increase in survival rate; however, there are not enough radiologists to serve the growing population of women seeking screening mammography. Although commercial computer aided detection (CADe) software has been available to radiologists for decades, it has failed to improve the interpretation of full-field digital mammography (FFDM) images due to its low sensitivity over the spectrum of findings. In this work, we leverage a large set of FFDM images with loose bounding boxes of mammographically significant findings to train a deep learning detector with extreme sensitivity. Building upon work from the Hourglass architecture, we train a model that produces segmentation-like images with high spatial resolution, with the aim of producing 2D Gaussian blobs centered on ground-truth boxes. We replace the pixel-wise $L_2$ norm with a weak-supervision loss designed to achieve high sensitivity, asymmetrically penalizing false positives and false negatives while softening the noise of the loose bounding boxes by permitting a tolerance in misaligned predictions. The resulting system achieves a sensitivity for malignant findings of 0.99 with only 4.8 false positive markers per image. When utilized in a CADe system, this model could enable a novel workflow where radiologists can focus their attention with trust on only the locations proposed by the model, expediting the interpretation process and bringing attention to potential findings that could otherwise have been missed. Due to its nearly perfect sensitivity, the proposed detector can also be used as a high-performance proposal generator in two-stage detection systems.
Traditional sentiment analysis approaches tackle problems like ternary (3-category) and fine-grained (5-category) classification by learning the tasks separately. We argue that such classification tasks are correlated and we propose a multitask approach based on a recurrent neural network that benefits by jointly learning them. Our study demonstrates the potential of multitask models on this type of problems and improves the state-of-the-art results in the fine-grained sentiment classification problem.
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