The VST Optical Imaging of the CDFS and ES1 Fields (VOICE) Survey is a Guaranteed Time program carried out with the ESO/VST telescope to provide deep optical imaging over two 4 deg$^2$ patches of the sky centred on the CDFS and ES1 pointings. We present the cosmic shear measurement over the 4 deg$^2$ covering the CDFS region in the $r$-band using LensFit. Each of the four tiles of 1 deg$^2$ has more than one hundred exposures, of which more than 50 exposures passed a series of image quality selection criteria for weak lensing study. The $5sigma$ limiting magnitude in $r$- band is 26.1 for point sources, which is $sim$1 mag deeper than other weak lensing survey in the literature (e.g. the Kilo Degree Survey, KiDS, at VST). The photometric redshifts are estimated using the VOICE $u,g,r,i$ together with near-infrared VIDEO data $Y,J,H,K_s$. The mean redshift of the shear catalogue is 0.87, considering the shear weight. The effective galaxy number density is 16.35 gal/arcmin$^2$, which is nearly twice the one of KiDS. The performance of LensFit on such a deep dataset was calibrated using VOICE-like mock image simulations. Furthermore, we have analyzed the reliability of the shear catalogue by calculating the star-galaxy cross-correlations, the tomographic shear correlations of two redshift bins and the contaminations of the blended galaxies. As a further sanity check, we have constrained cosmological parameters by exploring the parameter space with Population Monte Carlo sampling. For a flat $Lambda$CDM model we have obtained $Sigma_8$ = $sigma_8(Omega_m/0.3)^{0.5}$ = $0.68^{+0.11}_{-0.15}$.
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