We study the impact of finite-size effects on the key rate of continuous-variable (CV) measurement-device-independent (MDI) quantum key distribution (QKD). Inspired by the parameter estimation technique developed in [Rupert textit{et al.} Phys. Rev. A textbf{90}, 062310 (2014)]~we adapt it to study CV-MDI-QKD and, assuming realistic experimental conditions, we analyze the impact of finite-size effects on the key rate. We find that, increasing the block-size, the performance of the protocol converges towards the ideal one, and that block-sizes between $10^{6}$ and $10^{9}$ data points can already provide a key rate $sim10^{-2}$ bit/use over metropolitan distances.