Dawn-dusk asymmetries are ubiquitous features of the coupled solar-wind-magnetosphere-ionosphere system. During the last decades, increasing availability of satellite and ground-based measurements has made it possible to study these phenomena in more detail. Numerous publications have documented the existence of persistent asymmetries in processes, properties and topology of plasma structures in various regions of geospace. In this paper, we present a review of our present knowledge of some of the most pronounced dawn-dusk asymmetries. We focus on four key aspects: (1) the role of external influences such as the solar wind and its interaction with the Earths magnetosphere; (2) properties of the magnetosphere itself; (3) the role of the ionosphere and (4) feedback and coupling between regions. We have also identified potential inconsistencies and gaps in our understanding of dawn-dusk asymmetries in the Earths magnetosphere and ionosphere.
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