One of the most important task in physics today is to merge quantum mechanics and general relativity into one framework. And the main barrier in this task is that we lack quantum gravitational phenomena in experiments. An important way to get quantum gravitational phenomena is to study quantum effects in a macro-scale system in which gravity will play a role. In this article, we want to study dynamics of a possible macro-scale system: liquid helium droplets with radius of 100nm under low temperature and low pressure. Our idea is to observe the interference phenomenon of this system and find the similarities and difference between it and quantum system. We gave a practical experiment design to observe the interference, including a possible method to realize an approximate square barrier. We also gave an illustration on what a quantum or a classical interferogram of our system looks like theoretically.